Wool Clothing for Eczema
(DESSINE2 Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byJohn C Su, FACD, FRACP

Age: < 18

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: Murdoch Childrens Research Institute

No Placebo Group

Trial Summary

What is the purpose of this trial?

The study is a sequentially recruited, cross-over-cohort, outpatient-based evaluation of the effectiveness of wool clothing, as compared to standard clothing, in reducing the severity of childhood atopic dermatitis (eczema) over two consecutive six-week periods.

Eligibility Criteria

This trial is for children aged 3 months to 5 years with moderate to severe eczema (EASI score of 7+). They must have a guardian who can consent for them. Kids who've used strong allergy meds in the last 6 weeks, can't attend all visits, are allergic to wool, or whose eczema isn't stable aren't eligible.

Inclusion Criteria

I am between 3 months and 5 years old.

My eczema is moderate to severe, with an EASI score over 7.

I have someone who can legally consent for me.

Exclusion Criteria

I cannot attend all the scheduled visits.

You are allergic to wool or merino wool.

Any medical reason that is considered by the principal investigator to preclude enrollment

See 2 more

Treatment Details

Interventions

Standard Clothing (Other)
Wool Clothing (Behavioural Intervention)

Trial OverviewThe study compares the effects of wearing wool clothing versus standard clothing on reducing childhood eczema severity over two six-week periods. It's an outpatient study where participants switch from one type of clothing to another halfway through.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: wool-first (wool X standard)Experimental Treatment2 Interventions

superfine merino wool clothing to be worn for 6 weeks followed by 6 weeks of standard clothing

Group II: standard-first (standard X wool)Active Control2 Interventions

standard clothing to be worn for 6 weeks followed by 6 weeks of superfine merino wool clothing