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Exercise for Obesity

N/A

Waitlist Available

Led By Laurie J Goodyear, PhD

Research Sponsored by Joslin Diabetes Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age: 25-55 years old at the time of screening

Be between 18 and 65 years old

Must not have

Age <25 and >55 years old

Basal-Bolus Insulin regimen

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from baseline adipose tissue characteristics following 10 weeks of exercise training.

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether exercise can improve how well the body regulates blood sugar and body weight.

Who is the study for?

This trial is for adults aged 25-55 with varying body weights and conditions: healthy, overweight, obese, or with type 2 diabetes. Participants should have a BMI within certain ranges depending on their health status and controlled HbA1c levels. Those pregnant, on specific medications, with severe hypertension or other serious health issues are excluded.

What is being tested?

The study investigates how exercise affects white adipose tissue (body fat) in relation to sugar regulation and weight control. It aims to understand if regular physical activity can lead to beneficial changes in the body's handling of sugar among different groups of people.

What are the potential side effects?

Since this trial involves an exercise intervention rather than medication, side effects may include typical responses to physical activity such as muscle soreness, fatigue or injury risk. However, these will vary based on individual fitness levels and the intensity of the exercise regimen.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 25 and 55 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am younger than 25 or older than 55 years old.

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I am on a basal-bolus insulin treatment plan.

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I currently have a fever, body aches, or swollen glands due to an infection.

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I have kidney or liver problems.

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My blood pressure is not higher than 160/90 mmHg.

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I have Type 1 Diabetes.

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I have a heart or lung condition.

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I have had a stroke in the past.

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I have a history of HIV/AIDS or certain cancers.

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I do not have multiple sclerosis or ALS.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from baseline adipose tissue characteristics following 10 weeks of exercise training.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from baseline adipose tissue characteristics following 10 weeks of exercise training.

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline adipose tissue characteristics following 10 weeks of exercise training. for reporting.