Air Purification for Eosinophilic COPD

Recruiting in Palo Alto (17 mi)

Overseen byMary B Rice, MD MPH

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Beth Israel Deaconess Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial is testing if using home air purifiers can help adults with a specific type of COPD by cleaning the air they breathe. The goal is to see if this improves their lung health and reduces symptoms.

Eligibility Criteria

Adults over 40 with eosinophilic COPD, a history of smoking (at least 10 pack-years), and specific lung function test results can join. They must not already use HEPA air purifiers, live in long-term care, plan to move soon, or have severe diseases with less than 2 years life expectancy.

Inclusion Criteria

I have been diagnosed with moderate to severe COPD.

I am 40 years old or older.

Blood eosinophil count of >=150 cells per μL at screening or in the previous year

+1 more

Exclusion Criteria

My doctor thinks I have less than 2 years to live due to a severe illness.

I cannot perform lung function tests.

Living in location other than home (e.g. long term care facility)

+3 more

Participant Groups

The trial is testing if home air purifiers improve lung health in people with eosinophilic COPD. Participants are randomly divided into two groups: one gets real HEPA filter air purifiers and the other gets fake ones.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: True air purifierExperimental Treatment1 Intervention

Participants will receive a HEPA air purifier in the bedroom and living room.

Group II: Sham air purifierPlacebo Group1 Intervention

Participants will receive a sham air purifier that will be installed in the bedroom and living room. These purifiers will make a noise, but will not filter the air.