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Behavioural Intervention

Brain Stimulation for Muscle Fatigue

N/A
Waitlist Available
Research Sponsored by University of Nevada, Las Vegas
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Free from any neurological or psychiatric condition
Age between 18-50 years old
Must not have
An uncontrolled medical condition (i.e. hypertension, diabetes, etc)
Hearing loss diagnosed by a doctor and requiring a hearing aid
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 5 months
Awards & highlights

Summary

This trial aims to study if a type of brain stimulation called transcranial direct current stimulation (tDCS) on a specific part of the brain can reduce muscle fatigue. They want to find out

Who is the study for?
This trial is for individuals experiencing muscle fatigue. Participants will undergo two sessions about a week apart, where they'll do strength tests and a task that causes muscle tiredness.
What is being tested?
The study is testing if stimulating the brain's dorsolateral prefrontal cortex with electricity (tDCS) can help muscles stay strong longer during tiring activities, compared to fake stimulation (SHAM).
What are the potential side effects?
Possible side effects of tDCS may include mild tingling, itching or discomfort at the electrode site on the head, headache, fatigue, nausea or dizziness.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I do not have any mental health or neurological conditions.
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I am between 18 and 50 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have a medical condition that is not well-managed.
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I have doctor-diagnosed hearing loss and use a hearing aid.
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I have a history of brain-related health issues, including seizures or head injuries.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~5 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Fatigue Index
Time to Task Failure
Secondary study objectives
9 Hole Pegboard Test
Average EMG activity
Force error
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: tDCSExperimental Treatment1 Intervention
Transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex
Group II: SHAMPlacebo Group1 Intervention
SHAM transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
transcranial direct current stimulation
2013
Completed Phase 3
~1430

Find a Location

Who is running the clinical trial?

University of Nevada, Las VegasLead Sponsor
70 Previous Clinical Trials
13,968 Total Patients Enrolled
~13 spots leftby Sep 2025