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MRI for Heart Failure

N/A
Recruiting
Led By Joao AC Lima, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Age: 21 years and above.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from enrollment up to 30 days post treatment
Awards & highlights
No Placebo-Only Group

Summary

This trial investigates the relationship between heart failure and changes in brain structure. Patients with heart failure are at a higher risk of dementia and show brain alterations. Reduced blood flow to the brain is thought to be

Who is the study for?
This trial is for adults over 21 who can walk on their own and have heart failure with an ejection fraction below 50%. They must not be claustrophobic to undergo MRI scans. Participants need to give informed consent.
What is being tested?
The study uses MRI imaging, with or without contrast, to measure brain volumes in people with heart failure. It aims to find links between the size of certain brain areas and heart function, comparing these findings with those from healthy hearts.
What are the potential side effects?
MRI scans are generally safe but may cause discomfort due to loud noises or lying still. If contrast is used, there's a small risk of allergic reaction or kidney issues in susceptible individuals.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 21 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from enrollment up to 30 days post treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and from enrollment up to 30 days post treatment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Subcortical Volumes in Heart Failure

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Non-HospitalizedExperimental Treatment1 Intervention
Participants who had heart failure (HF) but did not require hospitalization secondary to the illness.
Group II: HospitalizedExperimental Treatment1 Intervention
Participants who were hospitalized due to heart failure (HF) illness.

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Who is running the clinical trial?

Canon Medical Systems, USAIndustry Sponsor
13 Previous Clinical Trials
1,184 Total Patients Enrolled
Johns Hopkins UniversityLead Sponsor
2,339 Previous Clinical Trials
14,881,531 Total Patients Enrolled
24 Trials studying Heart Failure
9,929 Patients Enrolled for Heart Failure
Joao AC Lima, MDPrincipal InvestigatorJohns Hopkins University
2 Previous Clinical Trials
50 Total Patients Enrolled
Joao Lima, MDPrincipal InvestigatorJohns Hopkins University
1 Previous Clinical Trials
210 Total Patients Enrolled
~67 spots leftby Oct 2026
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