Ambient Heating for Heat Stress

N/A

Recruiting

Led By Craig Crandall, Ph.D.

Research Sponsored by University of Texas Southwestern Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Current smokers, as well as individuals who regularly smoked within the past 3 years

Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc.; as well as serious abnormalities detected on routine screening

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 hour 20 minutes into the the heat intervention.

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to compare how the skin temperature changes in response to heat stress with and without cooling methods.

Who is the study for?

This trial is for healthy individuals without significant medical issues, as determined by a detailed medical history and physical exam. Participants must have a normal resting electrocardiogram. It's not suitable for those with underlying health problems that could affect their response to heat stress.

What is being tested?

The study aims to observe how skin surface and deeper skin temperatures react to being heated up in different conditions—with and without the help of sweat (evaporative cooling) and air movement (convective cooling).

What are the potential side effects?

Since this trial involves exposure to heat stress, potential side effects may include symptoms related to overheating such as sweating, dehydration, dizziness, or mild heat-related illnesses.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am a current smoker or have smoked regularly in the last 3 years.

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I have a chronic condition like heart disease, diabetes, or high blood pressure that needs regular treatment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 hour 20 minutes into the the heat intervention.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 hour 20 minutes into the the heat intervention.

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 hour 20 minutes into the the heat intervention. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Skin Temperature with Fan Only

Skin Temperature with Fan and Water Spray

Skin Temperature with No Cooling

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Healthy Adults ArmExperimental Treatment1 Intervention

Healthy Subject will rest in an environmental chamber that is no hotter than 47°C (117 °F). While in the chamber, the study team will periodically use a water spray to wet subject's skin and turn on an electric fan. During this time, the temperature of skin on arm using a temperature probe placed on the surface of skin and another temperature probe placed within skin (intradermal) will be monitored.

0 / 2Eligibility criteria met