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Sit-stand Desk for Diabetes Prevention

N/A
Recruiting
Research Sponsored by Medical College of Wisconsin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
An employee of the Medical College of Wisconsin with 'sedentary' jobs, defined as spending at least 75% of their (8 hours or more) workday sitting at a desk (at home or in an office)
Be older than 18 years old
Must not have
Positional syncope or history of orthostasis
Established congestive heart failure or cardiomyopathy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 6 months and baseline to 3 months changes
Awards & highlights
No Placebo-Only Group

Summary

This trial will assess if using a sit-stand desk when working from home can help prevent diabetes.

Who is the study for?
This trial is for sedentary workers at the Medical College of Wisconsin with a BMI over 25, who are at risk for type 2 diabetes due to factors like family history or prediabetes. Participants should not be currently using a standing desk, have no major cardiovascular diseases, musculoskeletal disorders, uncontrolled hypertension, or other specific health conditions.
What is being tested?
The study tests if sit-stand desks can improve insulin sensitivity and metabolic health in office workers at risk for diabetes. It randomly assigns participants to use the desk either 2 or 3 hours daily or to a control group without this intervention over six months while monitoring their activity levels.
What are the potential side effects?
There may be minimal side effects from participating in this trial as it involves lifestyle changes rather than medication. However, some individuals might experience discomfort or fatigue from increased standing times.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I work at the Medical College of Wisconsin and spend most of my day sitting.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have fainted or felt dizzy when standing up.
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I have been diagnosed with heart failure or cardiomyopathy.
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I have a history of serious heart disease.
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I have diabetes with HbA1c levels of 6.5% or higher, or I am on diabetes medication.
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I have nerve damage from any cause.
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I have been diagnosed with peripheral vascular disease.
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I have long-term joint pain in my legs or use aids like a walker.
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I use steroids for more than 21 days a year.
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I work less than 4 days a week at one place or from home.
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My blood pressure is controlled and below 150/90 mm Hg.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 6 months and baseline to 3 months changes
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 6 months and baseline to 3 months changes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Insulin sensitivity (HOMA-IR)
Secondary study objectives
Insulin
fasting triglycerides, very low density lipoprotein (VLDL)
Metabolic Syndrome X
+1 more
Other study objectives
Acceptability Questionnaire
free fatty acids

Side effects data

From 2012 Phase 4 trial • 200 Patients • NCT01342510
30%
Pain with injection of propofol
100%
80%
60%
40%
20%
0%
Study treatment Arm
Lidocaine/Magnesium
Control
Lidocaine
Magnesium

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: ControlExperimental Treatment1 Intervention
Subjects will not receive a sit/stand desk for the duration of the study and will be asked to follow their normal work day routine.
Group II: 2-Hour GroupActive Control1 Intervention
Sit-stand desk intervention group, subjects are asked to maintain the desk in the standing position at LEAST 2 hours each work day.
Group III: 3-Hour GroupActive Control1 Intervention
Sit-stand desk intervention group, subjects are asked to maintain the desk in the standing position at LEAST 3 hours each work day.

Find a Location

Who is running the clinical trial?

Medical College of WisconsinLead Sponsor
631 Previous Clinical Trials
1,181,758 Total Patients Enrolled

Media Library

Sit-stand desk intervention Clinical Trial Eligibility Overview. Trial Name: NCT05585190 — N/A
Metabolic Syndrome Research Study Groups: Control, 2-Hour Group, 3-Hour Group
Metabolic Syndrome Clinical Trial 2023: Sit-stand desk intervention Highlights & Side Effects. Trial Name: NCT05585190 — N/A
Sit-stand desk intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT05585190 — N/A
~128 spots leftby Dec 2027
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