~28 spots leftby Sep 2025

Self-Help Program for Emotional Distress Due to Infertility

Recruiting in Palo Alto (17 mi)
JL
Overseen byJennifer L. Gordon, Ph.D.
Age: 18+
Sex: Female
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of Regina
No Placebo Group

Trial Summary

What is the purpose of this trial?

Now affecting one in six couples in Canada, infertility is defined as a lack of conception after 12 or more months of regular, unprotected sexual intercourse. Infertility can result from a number of causes; however, women are responsible for accommodating rigid treatment regimens and carry a disproportionate share of the psychological burden associated with infertility. Thirty to forty percent of women presenting for the evaluation of infertility experiencing clinically significant depression or anxiety. Yet access to infertility-specific mental health resources is extremely limited in Canada; current psychological interventions are not specialized to this population and are largely ineffective at reducing distress. Therefore, there is an enormous need to increase the efficacy and accessibility of mental health resources for this population. To address this need, the 7-week Coping with Infertility (CWI) program was developed in collaboration with women with lived experience with infertility. The CWI program aims to reduce distress related to infertility and was recently tested in a small pilot study, where it was found to be very effective in reducing depression and anxiety and improving quality of life among individuals struggling to get pregnant. The goal of this clinical study is to test the CWI program in adult women experiencing infertility. The main questions it aims to answer are if the CWI program is effective at improving mental health and well-being in women experiencing infertility, and if demographic or lifestyle factors moderate the effect of the treatment. For seven weeks, participants will receive the CWI program and complete online questionnaires and interviews to assess the program's effects on infertility-related distress, quality of life, depressive symptoms, anxiety, and relationship quality. They will then complete these questionnaires biweekly for 16 weeks following the program. Researchers will compare the CWI program to a waitlist/treatment as usual control condition to see if the program reduces psychological distress above and beyond women's ordinary coping strategies. If the program is effective in improving psychological well-being in this clinical study, the researchers will make the program widely and freely available to women throughout Canada and the world.

Research Team

JL

Jennifer L. Gordon, Ph.D.

Principal Investigator

Unviersity of Regina

Eligibility Criteria

This trial is for adult women who have been trying to conceive for over a year or are undergoing fertility treatments, and can communicate fluently in English. It's not suitable for those under 18 years old.

Inclusion Criteria

Fluent in English
Experiencing infertility (defined as lack of conception after 12 or more months of regular, unprotected, heterosexual intercourse, or currently undergoing fertility treatments)
I was assigned female at birth.

Exclusion Criteria

I am younger than 18 years old.

Treatment Details

Interventions

  • Coping with Infertility Self-Help Program (Behavioral Intervention)
Trial OverviewThe study tests the 'Coping with Infertility' (CWI) program, designed to help reduce emotional distress from infertility. Over seven weeks, participants will engage with this self-help program and their mental well-being will be assessed through questionnaires and interviews.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Intervention ConditionExperimental Treatment1 Intervention
This arm will receive the Coping with Infertility intervention.
Group II: Waitlist/Treatment as Usual Control ConditionActive Control1 Intervention
This arm will continue with everyday life-including their attempts to conceive.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Regina

Lead Sponsor

Trials
59
Recruited
9,100+

Dr. Jeff Keshen

University of Regina

Chief Executive Officer since 2021

PhD in Political Science from the University of Toronto

Dr. Cathy Rocke

University of Regina

Chief Medical Officer since 2020

PhD in Social Work from the University of Manitoba

University of Calgary

Collaborator

Trials
827
Recruited
902,000+
Dr. Shweta Patel profile image

Dr. Shweta Patel

University of Calgary

Chief Medical Officer since 2020

MD from the University of Baroda Medical College, India

Dr. Edward McCauley profile image

Dr. Edward McCauley

University of Calgary

President and Vice-Chancellor since 2018

PhD in Ecology and Evolutionary Biology from the University of California, Santa Barbara

Canadian Institutes of Health Research (CIHR)

Collaborator

Trials
1,417
Recruited
26,550,000+

Dr. Paul C. Hébert

Canadian Institutes of Health Research (CIHR)

Chief Executive Officer

MD, University of Ottawa

Dr. Paul C. Hébert

Canadian Institutes of Health Research (CIHR)

Chief Medical Officer

MD, University of Ottawa

Saskatchewan Health Research Foundation

Collaborator

Trials
33
Recruited
5,100+