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Probiotic

Greek Yogurt for Osteoporosis and Inflammation

N/A

Waitlist Available

Research Sponsored by Brock University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adults 55+ years from the Niagara area

Be older than 18 years old

Must not have

Diagnosed with lactose intolerance

Timeline

Screening 3 weeks

Treatment Varies

Follow Up weeks 0 and 8

Awards & highlights

No Placebo-Only Group

Summary

"This trial aims to see if eating Greek yogurt and doing regular exercise can improve bone health and reduce inflammation in older adults. They will compare a group that eats Greek yogurt and exercises, a group that only

Who is the study for?

This trial is for senior adults interested in the potential health benefits of Greek yogurt. Participants should be experiencing inflammation or osteoporosis and willing to consume Greek yogurt regularly. They must also be open to participating with or without accompanying regular exercise.

What is being tested?

The study tests if eating Greek yogurt can improve bone metabolism and reduce inflammation in seniors, comparing groups who exercise (GYEX), don't exercise (GYNE), and a control group that only exercises without yogurt (NYEX).

What are the potential side effects?

Greek yogurt is generally safe but may cause digestive discomfort, such as bloating or gas, especially in those with lactose intolerance or dairy sensitivity.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 55 years old or older and live in the Niagara area.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have been diagnosed with lactose intolerance.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ weeks 0 and 8

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~weeks 0 and 8

This trial's timeline: 3 weeks for screening, Varies for treatment, and weeks 0 and 8 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Plasma concentrations of interleukin-10 (IL10)

Plasma concentrations of interleukin-6 (IL6)

Serum concentrations of C-telopeptides of type I collagen (CTX)

+9 more

Secondary study objectives

Body composition

Body mass

Energy intake and expenditure

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Greek yogurt exercising group (GYEX)Experimental Treatment1 Intervention

Participants will be asked to consume 2 servings/day (preferably morning and night) of 175 g commercially available GY (0% MF, flavoured, 130 calories, 17 g protein, 225 g calcium (e.g., OIKOS High Protein GY) for a total of 8 weeks. For their convenience, the participants will be provided with appropriate scoops to measure out 175 g of GY per serving of the larger 650 g commercially available, pre-packaged containers. Although it is recommended to consume the two servings morning and night, to increase ecological validity and strengthen the feasibility of the intervention, the timing of the servings will be flexible to facilitate daily routines and lifestyles. For the same reasons, the participants will be able to choose the flavour of their GY.

Group II: Control exercising group (NYEX)Active Control1 Intervention

During the 8-weeks, participants will be instructed to follow their typical, habitual diet and exercise regimen.

Group III: Intervention non-exercising group (GYNE)Active Control1 Intervention

Participants will be instructed to follow their typical habitual diet. Participants will be asked to consume 2 servings/day (preferably morning and night) of 175 g commercially available GY (0% MF, flavoured, 130 calories, 17 g protein, 225 g calcium; e.g., OIKOS High Protein GY) for a total of 8 weeks. For their convenience, the participants will be provided with appropriate scoops to measure out 175 g of GY per serving of the larger 650 g commercially available, pre-packaged containers. Although it is recommended to consume the two servings morning and night, to increase ecological validity and strengthen the intervention's feasibility, the servings' timing will be flexible to facilitate daily routines and lifestyles. For the same reasons, the participants will be able to choose the flavour of their GY.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Greek yogurt

2011

N/A

~60

0 / 2Eligibility criteria met