Intraocular Pressure Measurement for Glaucoma

Recruiting in Palo Alto (17 mi)

Overseen by Mathieu Caissie, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: CHU de Quebec-Universite Laval

Disqualifiers: Corneal dystrophy, Corneal surgery, others

No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this prospective controlled study is to measure the reliability of two intraocular pressure (IOP)-measuring instruments in comparison to the gold standard, Goldmann applanation tonometry (GAT) following vitreo-retinal surgery. The main question the current study aims to answer is: are Icare and Accupen as accurate as GAT in measuring IOP one day post eye surgery? Participants in this study will have their IOP measured by the three different instruments one day post-surgery.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Intraocular pressure measure, Goldmann Applanation Tonometry, Icare, Accupen for glaucoma?

Research shows that the Icare tonometer, a device used to measure eye pressure, provides results that are in agreement with the Goldmann Applanation Tonometer, which is a standard method for measuring intraocular pressure. This suggests that Icare is effective for monitoring eye pressure in conditions like glaucoma.

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Is intraocular pressure measurement safe for humans?

The studies on intraocular pressure measurement using devices like ICare and Goldmann Applanation Tonometry focus on comparing their accuracy and reliability, but they do not report any safety concerns, suggesting these methods are generally safe for human use.

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How does the treatment for measuring intraocular pressure in glaucoma differ from other treatments?

The treatment for measuring intraocular pressure in glaucoma, using devices like the Goldmann Applanation Tonometry and iCare, is unique because it focuses on accurately measuring eye pressure rather than treating the condition directly. These devices are non-invasive and portable, making them convenient for regular monitoring, unlike other treatments that may involve medication or surgery to manage glaucoma.

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Eligibility Criteria

This trial is for individuals who have undergone vitreoretinal surgery and need their intraocular pressure (IOP) measured the following day. The study aims to include participants who can safely undergo IOP measurements with different instruments.

Inclusion Criteria

I am 18 years old or older.

I have had eye surgery on the retina.

Exclusion Criteria

I have not had corneal surgery in the last 6 months.

I have been diagnosed with corneal dystrophy.

I have had a scleral buckle procedure.

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Post-operative Measurement

Participants have their intraocular pressure measured by Goldmann applanation tonometry, Icare, and Accupen one day after vitreo-retinal surgery

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the post-operative measurement

2-4 weeks

Participant Groups

The study is testing the accuracy of two IOP-measuring devices, Icare and Accupen, against the gold standard Goldmann applanation tonometry (GAT), after eye surgery. Participants will have their IOP checked by all three methods one day post-operation.

Group I: Intraocular pressure measure Experimental Treatment 1 Intervention

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Hôpital du Saint-Sacrement, CHU de Québec - Université Laval Québec, Canada

Who Is Running the Clinical Trial?

CHU de Quebec-Universite Laval Lead Sponsor

References

1. United States pubmed.ncbi.nlm.nih.gov

Correlation of iCare ic100 tonometry with iCare TA01i in screening of unselected population in Northern Finland Birth Cohort Eye study. [2022] iCare tonometers are easy-to-use and portable devices for measuring the intraocular pressure (IOP). Purpose was to evaluate the IOP values measured by both novel iCare ic100 and conventional model TA01i devices in unselected population.

2. United States pubmed.ncbi.nlm.nih.gov

Validity and limits of the rebound tonometer (ICare®): clinical study. [2019] The aim of this study was to evaluate the measurement of intraocular pressure (IOP) using a new induction/impact rebound tonometer (ICare®) compared with Goldmann applanation tonometry (GAT). We also aimed to quantify the systematic and random errors (bias) of the 2 methods, to evaluate the sensitivity and specificity of the ICare® tonometer in identifying patients with 21 mmHg or more measured with the GAT, and to study the influence of corneal thickness on IOP measurement with the 2 tonometers.

3. United States pubmed.ncbi.nlm.nih.gov

Agreement of Intraocular Pressure Measurement of Icare ic200 with Goldmann Applanation Tonometer in Adult Eyes with Normal Cornea. [2021] To study the agreement between the Icare ic200 (ICare Finland Oy, Helsinki, Finland) and the Goldmann Applanation Tonometer (GAT) in the measurement of intraocular pressure (IOP) in adult eyes.

4. United States pubmed.ncbi.nlm.nih.gov

Agreement of Intraocular Pressure Measurement of Icare ic200 with Goldmann Applanation Tonometer in Adult Eyes with Normal Cornea. [2021] To study the agreement between the Icare ic200 (ICare Finland Oy, Helsinki, Finland) and the Goldmann Applanation Tonometer (GAT) in the measurement of intraocular pressure (IOP) in adult eyes.

5. United States pubmed.ncbi.nlm.nih.gov

Icare ONE rebound versus Goldmann applanation tonometry in children with known or suspected glaucoma. [2015] To compare Icare ONE tonometry by clinic examiner and parent/guardian to Goldmann applanation in children with known/suspected glaucoma; to evaluate the trend in intraocular pressure (IOP) with 4 repeated measurements using Icare ONE; and to evaluate the feasibility of instructing parents on the use of the Icare ONE device in the clinic setting.

6. England pubmed.ncbi.nlm.nih.gov

Comparison of intraocular pressure measured by iCare tonometers and Goldmann applanation tonometer. [2023] To evaluate the relationship between the Goldmann applanation tonometer (GAT) and the iCare PRO and iCare IC200 tonometers in measuring intraocular pressure (IOP) in adult eyes with a diagnosis of glaucoma or glaucoma suspect.

7. England pubmed.ncbi.nlm.nih.gov

Comparison of the ICare rebound tonometer with the Goldmann tonometer in a normal population. [2022] The aim of this study was to evaluate the accuracy of measurement of intraocular pressure (IOP) using a new induction/impact rebound tonometer (ICare) in comparison with the Goldmann applanation tonometer (AT). The left eyes of 46 university students were assessed with the two tonometers, with induction tonometry being performed first. The ICare was handled by an optometrist and the Goldmann tonometer by an ophthalmologist. In this study, statistically significant differences were found when comparing the ICare rebound tonometer with applanation tonometry (AT) (p

8. England pubmed.ncbi.nlm.nih.gov

Comparison of the ICare rebound tonometer with the Goldmann applanation tonometer by experienced and inexperienced tonometrists. [2022] To assess the agreement between ICare rebound tonometer and Goldmann applanation tonometer in the hands of experienced and inexperienced tonometrists.

9. England pubmed.ncbi.nlm.nih.gov

Comparison of the new rebound tonometer with Goldmann applanation tonometer in a clinical setting. [2022] To evaluate the clinical usefulness of a new rebound tonometer, Icare(®) PRO (Icare PRO), by comparison with Goldmann applanation tonometry (GAT) in a study on patients with glaucoma.

10. Germany pubmed.ncbi.nlm.nih.gov

Comparison of the iCare rebound tonometer and the Goldmann applanation tonometer over a wide IOP range. [2018] The aim of this study was to compare the intraocular pressure (IOP) results measured by the iCare rebound tonometer with those obtained by the Goldmann applanation tonometer (GAT) over a wide range of IOP values. Furthermore, the comfort level of the iCare measurement was evaluated.

11. United States pubmed.ncbi.nlm.nih.gov

Schiotz Scleral Intraocular Pressure Readings Predict Goldmann Applanation Readings Better Than Rebound Tonometry. [2019] To study the agreement between scleral intraocular pressure (IOP) measurements using the Schiotz, Icare, and Icare PRO tonometers versus Goldmann applanation tonometer (GAT) in eyes with nonscarred corneas.