← Back to Search

Behavioural Intervention

Bright Light Therapy for IBS

N/A

Recruiting

Led By Caitlin Green

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age between 18-65 years old

Diagnosed with Irritable Bowel Syndrome based on Rome IV diagnostic criteria

Must not have

Diagnosis of narrow angle glaucoma or retinal disorders, or demonstrated symptoms indicative of these diagnoses during eligibility screening

Presence of any major organ disease such as known renal impairment, diabetes, liver disease, significant cardiac failure (NY classification stage III/IV), inflammatory bowel disease, or celiac disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks of morning bright light therapy (blt)

Summary

This trial aims to see if using a wearable device called Re-Timer, which emits blue-green light therapy in the morning, can help improve symptoms of Irritable Bowel Syndrome (IBS) and

Who is the study for?

This trial is for individuals with Irritable Bowel Syndrome (IBS), who may also have Klinefelter or Triple X Syndrome. It's not clear what the specific inclusion and exclusion criteria are, but typically participants would need to meet certain health standards and not have conditions that could interfere with the study.

What is being tested?

The study is testing if morning bright light therapy using Re-Timer glasses can improve IBS symptoms and reduce leaky gut. Participants will wear these safe, lightweight glasses that emit blue-green light similar to natural sunlight.

What are the potential side effects?

While side effects are not detailed here, bright light therapy can sometimes cause eye strain, headache, nausea, irritability or sleep disturbances in some people.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 65 years old.

Select...

I have been diagnosed with Irritable Bowel Syndrome.

Select...

I have IBS with symptoms that are at least mild in severity.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have been diagnosed with or shown symptoms of narrow angle glaucoma or retinal disorders.

Select...

I do not have major organ diseases like kidney, liver issues, severe heart failure, or severe digestive conditions.

Select...

I have moderate to severe depression.

Select...

My restless leg syndrome is severe.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks of morning bright light therapy (blt)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks of morning bright light therapy (blt)

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks of morning bright light therapy (blt) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Aim 1a

Aim 1b

Secondary study objectives

Aim 2

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Re-Timer Device (Bright Light Therapy)Experimental Treatment1 Intervention

Morning bright light therapy will be administrated through a safe wearable device called a Re-timer. The Re-Timer glasses are lightweight and deliver blue-green light at 500nm, mimicking exposure to natural light. The device emits light at a higher wavelength than the UV range and has a UV filter for added safety. Subjects will be asked to wear the glasses for one hour each morning per day for 7 days a week. They will wear the device for a total of 14 days to receive the full therapeutic effect. Additionally, subjects will be asked to complete the light therapy the first hour of being awake and remain indoors while using the device. Participants will be informed that they can wear the device freely throughout their home or work environment but should avoid activities that could potentially be harmful (i.e., driving, contact sports, operating heavy machinery).

Group II: Placebo device (non Bright Light Therapy)Placebo Group1 Intervention

Subjects will be asked to wear glasses that do not provide Bright Light Therapy for one hour each morning per day for 7 days a week as recommended by the manufacturer. They will wear the device for a total of 14 days to receive the full therapeutic effect. Additionally, subjects will be asked to complete the light therapy the first hour of being awake and remain indoors while using the device. Participants will be informed that they can wear the device freely throughout their home or work environment but should avoid activities that could potentially be harmful (i.e., driving, contact sports, operating heavy machinery).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Re-Timer glasses

2015

N/A

~20

0 / 7Eligibility criteria met