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Lifestyle Physical Activity for Metabolic Diseases

N/A

Waitlist Available

Led By Marc T Hamilton, Ph.D.

Research Sponsored by University of Houston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age must be 18 years or older

Be older than 18 years old

Must not have

Taking medications that affect bleeding (ie anticoagulants).

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the change through the completion of an acute fasting period, approximately 8-12 hours

Awards & highlights

No Placebo-Only Group

Summary

This trial is designed to study the effects of a new way of doing light physical activity - what we are calling "lifestyle physical activity" (LPA) - on specific and systemic metabolism. LPA is designed to be safe and practical for people to do every day, for prolonged periods of time throughout the day, and to be done while performing their daily activities.

Who is the study for?

This trial is for adults over 18 who can fast overnight, maintain consistent diet, medication, and sleep habits. They should have a sedentary lifestyle but be willing to wear activity monitors and not start new diets or exercise programs during the study. Exclusions include practical barriers to participation, current dieting or eating disorders, allergies to lidocaine, pregnancy, use of anticoagulants, or plans to change lifestyle.

What is being tested?

The trial aims to develop a method that allows people with sedentary lifestyles to sustain muscle activity via oxidative metabolism for extended periods (hours daily). It involves controlled muscular exercises focusing on specific muscles like the soleus in the leg and measuring their biological response without causing fatigue.

What are the potential side effects?

Since this trial focuses on light physical activities designed for unfit individuals leading sedentary lives, side effects are expected to be minimal. However, typical exercise-related discomforts such as mild muscle soreness may occur.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am taking medication that affects bleeding.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the change through the completion of an acute fasting period, approximately 8-12 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the change through the completion of an acute fasting period, approximately 8-12 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and the change through the completion of an acute fasting period, approximately 8-12 hours for reporting.