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Behavioural Intervention

Smartphone App vs. Diabetes Prevention Program for Obesity (EVO Trial)

Chicago, IL
N/A
Recruiting
Led By Angela Pfammatter, PhD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
BMI 30-45
Be older than 18 years old
Must not have
Taking anti-obesity medications
Not taking medications that may cause weight gain
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights
No Placebo-Only Group

Summary

This trial will compare a new weight-loss program to the current gold standard to see which is more effective and cost-efficient.

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Who is the study for?
This trial is for adults with obesity, having a BMI between 30-45, who own and can use a smartphone. Participants should be willing to install an app and do video calls with the study team. It's not for those on weight loss programs, insulin-treated diabetes, recent psychiatric hospitalizations, moderate exercise-induced cardiovascular symptoms, pregnant or lactating women, Crohn's Disease sufferers, bulimia or binge eating disorders patients.Check my eligibility
What is being tested?
The study compares two methods to treat obesity: one group uses a specially designed smartphone app (APP) while the other follows the Diabetes Prevention Program (DPP). The goal is to see which method helps people lose more weight effectively and affordably.See study design
What are the potential side effects?
Since this trial involves lifestyle interventions rather than medications, side effects are minimal but may include potential stress or frustration from dietary changes or new exercise routines.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My BMI is between 30 and 45.
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Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am currently taking medication for weight loss.
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I am not on medications that can cause weight gain.
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I need insulin for my diabetes.
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I have Crohn's Disease.
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I have sleep apnea and need treatment like CPAP.
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I use devices like canes or walkers to help me move around.
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I have not been hospitalized for a mental health issue in the last 5 years.
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I experience heart problems when doing moderate exercise.
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I have thoughts of harming myself.
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Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Weight
Secondary study objectives
Costs of treatment

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Smartphone App Participants (APP)Experimental Treatment1 Intervention
Smartphone application, diet and activity goals, online lessons, brief remote sessions with a Health Promotionist
Group II: Diabetes Prevention Program Participants (DPP)Experimental Treatment1 Intervention
Participant program manual, diet and activity logs, hour long remote sessions with a Health Promotionist

Find a Location

Closest Location:Northwestern University· Chicago, IL· 276 miles

Who is running the clinical trial?

Washington University School of MedicineOTHER
2,022 Previous Clinical Trials
2,351,720 Total Patients Enrolled
86 Trials studying Obesity
15,302 Patients Enrolled for Obesity
Northwestern UniversityLead Sponsor
1,670 Previous Clinical Trials
987,322 Total Patients Enrolled
34 Trials studying Obesity
11,078 Patients Enrolled for Obesity
Angela Pfammatter, PhDPrincipal InvestigatorNorthwestern University
1 Previous Clinical Trials
492 Total Patients Enrolled
1 Trials studying Obesity
492 Patients Enrolled for Obesity

Media Library

Diabetes Prevention Program Participants (DPP) (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04708769 — N/A
Obesity Research Study Groups: Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
Obesity Clinical Trial 2023: Diabetes Prevention Program Participants (DPP) Highlights & Side Effects. Trial Name: NCT04708769 — N/A
Diabetes Prevention Program Participants (DPP) (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04708769 — N/A
Obesity Patient Testimony for trial: Trial Name: NCT04708769 — N/A
~154 spots leftby Nov 2026