Showmotion for Osteoarthritis

Recruiting in Palo Alto (17 mi)

Overseen by Vikas Patel, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: University of Colorado, Denver

Disqualifiers: Active infections, Surgery, BMI >30, Pregnancy

No Placebo Group

Approved in 2 Jurisdictions

Trial Summary

What is the purpose of this trial?

It is very important to understand joint and body kinematics and muscles activity in clinical settings, which is relevant to identify issues related to the spine, the upper and lower limbs due to injury. In this study, the investigators will use an innovative platform, Showmotion to establish baseline of shoulder, hip, knee and spine kinematics and muscles activity from 60 healthy volunteers.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Showmotion for osteoarthritis?

The MyArthritisRx.com platform, similar to Showmotion, showed that 92% of patients reported improvement in managing osteoarthritis after using a digital self-management program, suggesting that digital platforms can be effective in improving arthritis care. ^{1 2 3 4 5}

How is the Showmotion treatment for osteoarthritis different from other treatments?

There is no specific information available about Showmotion for osteoarthritis, but current treatments for osteoarthritis often focus on symptom management rather than modifying the disease itself. Showmotion might offer a novel approach if it involves a unique mechanism or administration method, but without more details, it's unclear how it differs from existing options. ^{6 7 8 9 10}

Research Team

Vikas Patel, MD

Principal Investigator

University of Colorado, Denver

Eligibility Criteria

This trial is for healthy individuals aged between 18 and 65 who can follow instructions and have given written consent. They should not be overweight (BMI over 30), pregnant, have had surgery on the joint of interest, or suffer from active infections.

Inclusion Criteria

Age > 18, <65

Volunteers given written informed consent

Ability to understand and execute instructions at all stages of the procedure

Exclusion Criteria

You have a body mass index (BMI) higher than 30, which means you are considered overweight.

You recently had surgery on the joint that is being studied.

Pregnancy

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Baseline Assessment

Establish baseline of shoulder, hip, knee, and spine kinematics and muscle activity using Showmotion

1 hour

1 visit (in-person)

Follow-up

Participants are monitored for any immediate reactions or data validation post-assessment

1 week

Treatment Details

Interventions

• Showmotion (Kinematics and Muscle Activity Evaluation)

Trial Overview The study is testing Showmotion, an innovative platform to measure how joints and muscles in the shoulder, hip, knee, and spine move and work in healthy volunteers to establish a baseline for future clinical use.

Participant Groups

Group I: Showmotion Experimental Treatment 1 Intervention

Performing an analysis requires the positioning of sensors on the patient's skin in predetermined positions, according to the related protocols. Each sensor positioned on patient's skin provides both raw data (accelerometer, magnetometer, gyroscope) and the orientation matrix, representing the orientation of the local System of Reference (SoR) with respect to a fixed SoR. A proprietary sensor-fusion algorithm allows provides an accurate estimate of the orientation, as assessed by stereo-photogrammetric system-based testing. Data from each sensor are sampled at 50 Hz and transferred wirelessly to a laptop with a proprietary software that processes the data according to the biomechanical model chosen for the analysis.

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

University of Colorado Anschutz Medical Campus Aurora, CO

Who Is Running the Clinical Trial?

University of Colorado, Denver

Lead Sponsor

Trials

1842

Patients Recruited

3,028,000+

Findings from Research

A digital management program for hip and knee osteoarthritis, which included education, exercises, and access to a physical therapist, was positively received by 19 participants, highlighting its flexibility and ease of access compared to traditional care.

Key benefits of the program included no waiting lists, the ability to participate from various locations at convenient times, and daily support from a physical therapist, making it a valid alternative for managing osteoarthritis.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

'I would never have done it if it hadn't been digital': a qualitative study on patients' experiences of a digital management programme for hip and knee osteoarthritis in Sweden. Cronström, A., Dahlberg, LE., Nero, H., et al.[2020]

References

1. United States pubmed.ncbi.nlm.nih.gov

A Digital Platform for the Self-Management of Knee Arthritis: MyArthritisRx.com. [2022]

2. Canada pubmed.ncbi.nlm.nih.gov

Effectiveness of a web-based physical activity intervention in patients with knee and/or hip osteoarthritis: randomized controlled trial. [2022]

3. Canada pubmed.ncbi.nlm.nih.gov

OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. [2022]

4. Canada pubmed.ncbi.nlm.nih.gov

Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017. [2023]

5. Canada pubmed.ncbi.nlm.nih.gov

The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. [2023]

6. England pubmed.ncbi.nlm.nih.gov

Potential directions for drug development for osteoarthritis. [2014]

7. England pubmed.ncbi.nlm.nih.gov

'I would never have done it if it hadn't been digital': a qualitative study on patients' experiences of a digital management programme for hip and knee osteoarthritis in Sweden. [2020]

8. Austria pubmed.ncbi.nlm.nih.gov

Radiological aspects of osteoarthritis. [2021]

9. Croatia pubmed.ncbi.nlm.nih.gov

[Osteoarthritis--epidemiology, economics and quality of life]. [2009]

10. England pubmed.ncbi.nlm.nih.gov

Glucosamine therapy for treating osteoarthritis. [2022]