Rapid POC Diagnostics for Strep Throat

Recruiting in Palo Alto (17 mi)

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Hamilton Health Sciences Corporation

No Placebo Group

Trial Summary

What is the purpose of this trial?

Randomized trial evaluating effectiveness of rapid point-of-care molecular GAS diagnostics as compared to standard culture-based techniques for the management of children aged 3-18 years of age presenting with sore throat to McMaster Children's Hospital Emergency Department.

Research Team

Eligibility Criteria

This trial is for children aged 3-18 who visit the McMaster Children's Hospital Emergency Department with a sore throat and need a GAS test. They can't have taken antibiotics effective against GAS in the last 72 hours.

Inclusion Criteria

All those presenting who have a throat swab ordered for GAS testing

Exclusion Criteria

You have taken antibiotics that work against GAS in the 3 days before going to the emergency department.

Treatment Details

Interventions

• Rapid testing (Molecular Diagnostics)
• Reference testing (Diagnostic Test)

Trial Overview The study compares rapid point-of-care molecular diagnostics for strep throat with standard culture-based tests to see which is more effective in diagnosing and managing the condition quickly.

Participant Groups

Group I: Rapid testing Experimental Treatment 1 Intervention

Abbott ID NOW Strep A testing.

Group II: Reference testing Active Control 1 Intervention

Culture-based testing.

Who Is Running the Clinical Trial?

Hamilton Health Sciences Corporation

Lead Sponsor

Trials

380

Recruited

345,000+

Dr. Craig A. VanHelder

Hamilton Health Sciences Corporation

Chief Medical Officer since 2023

MD

Tracey MacArthur

Hamilton Health Sciences Corporation

Chief Executive Officer

MSc in Quality Improvement & Patient Safety from the University of Toronto, Honours BA in Psychology from the University of Waterloo, Masters Certificate in Project Management from the Schulich School of Business at York University