Dutasteride + Dietary Interventions for Prostate Cancer

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byVincent Fradet, MD

Age: 18+

Sex: Male

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: CHU de Quebec-Universite Laval

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial is testing if a special diet with fish oils and a prostate medication can slow down cancer in men with low-risk prostate cancer. The fish oils may reduce inflammation, and the medication lowers hormones that help cancer grow.

Eligibility Criteria

This trial is for individuals with low-risk prostate cancer who are candidates for active surveillance and have given informed consent. It's not open to those currently taking fish oil supplements or NSAIDs.

Inclusion Criteria

My condition is being monitored rather than actively treated.

Informed consent

My prostate cancer is considered low risk.

Exclusion Criteria

I am currently taking NSAID medication.

Current fish oil supplementation

Participant Groups

The study is testing the effectiveness of marine omega-3 fatty acids (dietary intervention) and Dutasteride (a drug), separately, in slowing down the progression of low-risk prostate cancer.

2Treatment groups

Experimental Treatment

Group I: Drug intervention firstExperimental Treatment1 Intervention

Intake of 5α-Reductase Inhibitor

Group II: Dietary intervention firstExperimental Treatment1 Intervention

The dietary intervention will be aimed to increase intake of ω-3 long chain fatty acids and to reduce intake of saturated and trans fatty acids.