Trial Summary
What is the purpose of this trial?This trial involves patients taking a grape seed extract supplement to help manage their prostate health. The supplement is believed to protect cells and reduce inflammation. Patients' PSA levels will be monitored to assess the effectiveness of the treatment.
Eligibility Criteria
This trial is for adults over 18 with prostate cancer who've seen a rise in PSA after local therapy, not on active hormone therapies, and have declined or aren't candidates for salvage therapy. They must be able to swallow capsules, have no severe allergies to GSE products, and not be on surveillance for untreated localized disease.Inclusion Criteria
I am able to care for myself and perform daily activities.
My prostate cancer was confirmed through a tissue examination.
My PSA levels have increased on two tests done a week apart, with a baseline of at least 0.2 ng/mL, and I have no visible cancer on scans.
+13 more
Exclusion Criteria
My PSA levels are rising very quickly.
I cannot swallow pills or have a condition affecting my stomach's ability to absorb medicine.
I am not just being watched for my untreated localized disease.
+6 more
Participant Groups
The study tests the effects of Grape Seed Extract (GSE) taken orally at 150 mg twice daily. Participants will take GSE for up to one year with evaluations every six weeks initially and then every three months.
1Treatment groups
Experimental Treatment
Group I: 150 mg of Grape Seed Extract (GSE)Experimental Treatment1 Intervention
150 mg of GSE twice daily in the form of 75 mg capsule of Leucoselect Phytosome preparation.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
University of Colorado Cancer CenterAurora, CO
Poudre Valley HospitalFort Collins, CO
Loading ...
Who Is Running the Clinical Trial?
University of Colorado, DenverLead Sponsor
Cancer League of ColoradoCollaborator