Cognitive Rehabilitation for Multiple Sclerosis

N/A

Waitlist Available

Research Sponsored by Sunnybrook Health Sciences Centre

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

A define diagnosis of multiple sclerosis (which will include clinically isolate syndrome, radiologically isolated syndrome and neuromyelitis optica spectrum disorder)

Be older than 18 years old

Must not have

Unable or unwilling to travel to the Centre or requires transportation by ambulance

Use of illicit drugs, phencyclidine (PCP), Lysergic acid diethylamide (LSD), stimulants, amphetamines, barbiturates, etc. (Cannabis use is accepted)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 weeks immediate post assessment, and 6 months post assessment

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to improve the cognitive abilities of people with multiple sclerosis (MS) through a program called Goal Management Training (GMT). The study will have a treatment group that receives the GMT program and a

Who is the study for?

This trial is for individuals with Multiple Sclerosis who experience cognitive challenges, particularly in processing information, learning and memory, or executive function. Participants must be willing to undergo cognitive rehabilitation training.

What is being tested?

The study tests Goal Management Training (GMT) as a form of cognitive rehabilitation for MS patients. It's a randomized controlled trial where the treatment group receives GMT sessions over 5 weeks and their progress is compared to a wait-list control group receiving usual care.

What are the potential side effects?

Since the intervention involves non-invasive cognitive training exercises, no significant physical side effects are expected. However, participants may experience mental fatigue or frustration during the process.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with a form of multiple sclerosis.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I cannot travel to the Centre on my own or need an ambulance for transportation.

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I do not use illicit drugs except for cannabis.

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I have a history of a brain or spinal cord disease that is not multiple sclerosis.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 weeks immediate post assessment, and 6 months post assessment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 weeks immediate post assessment, and 6 months post assessment

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 weeks immediate post assessment, and 6 months post assessment for reporting.