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Maine Children's Cancer Program

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Scarborough, Maine 04074
Global Leader in Leukemia
Global Leader in Tumors
Conducts research for Lymphoblastic Leukemia-Lymphoma
Conducts research for Lymphoma
Conducts research for Brain Tumor
130 reported clinical trials
6 medical researchers
Photo of Maine Children's Cancer Program in ScarboroughPhoto of Maine Children's Cancer Program in Scarborough

Summary

Maine Children's Cancer Program is a medical facility located in Scarborough, Maine. This center is recognized for care of Leukemia, Tumors, Lymphoblastic Leukemia-Lymphoma, Lymphoma, Brain Tumor and other specialties. Maine Children's Cancer Program is involved with conducting 130 clinical trials across 268 conditions. There are 6 research doctors associated with this hospital, such as Eric C. Larsen, Aaron R. Weiss, Stanley Chaleff, MD, and Roger C. Inhorn.

Area of expertise

1Leukemia
Global Leader
Maine Children's Cancer Program has run 40 trials for Leukemia. Some of their research focus areas include:
Stage II
Stage IV
Stage III
2Tumors
Global Leader
Maine Children's Cancer Program has run 27 trials for Tumors. Some of their research focus areas include:
Stage IV
Stage I
Stage II

Top PIs

Clinical Trials running at Maine Children's Cancer Program

Brain Tumor
Osteosarcoma
Germ Cell Tumors
Astrocytoma
Non-Hodgkin's Lymphoma
Tumors
Acute Lymphoblastic Leukemia
Lymphoma
Rhabdomyosarcoma
Low Grade Glioma
Image of trial facility.

Selumetinib + Vinblastine

for Low-Grade Glioma

This phase III trial investigates the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine to selumetinib compared to selumetinib alone in treating children and young adults with low-grade glioma (a common type of brain cancer) that has come back after prior treatment (recurrent) or does not respond to therapy (progressive). Selumetinib is a drug that works by blocking a protein that lets tumor cells grow without stopping. Vinblastine blocks cell growth by stopping cell division and may kill cancer cells. Giving selumetinib in combination with vinblastine may work better than selumetinib alone in treating recurrent or progressive low-grade glioma.
Recruiting2 awards Phase 339 criteria
Image of trial facility.

Selumetinib vs Carboplatin/Vincristine

for Brain Cancer

This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatin/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in improving vision in subjects with LGG of the optic pathway (vision nerves). Selumetinib is a drug that works by blocking some enzymes that low-grade glioma tumor cells need for their growth. This results in killing tumor cells. Drugs used as chemotherapy, such as carboplatin and vincristine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether selumetinib works better in treating patients with NF1-associated low-grade glioma compared to standard therapy with carboplatin and vincristine.
Recruiting2 awards Phase 328 criteria
Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3

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Frequently asked questions

What kind of research happens at Maine Children's Cancer Program?
Maine Children's Cancer Program is a medical facility located in Scarborough, Maine. This center is recognized for care of Leukemia, Tumors, Lymphoblastic Leukemia-Lymphoma, Lymphoma, Brain Tumor and other specialties. Maine Children's Cancer Program is involved with conducting 130 clinical trials across 268 conditions. There are 6 research doctors associated with this hospital, such as Eric C. Larsen, Aaron R. Weiss, Stanley Chaleff, MD, and Roger C. Inhorn.