Transcranial Stimulation + Auditory Training for Hearing Loss
Recruiting0 awards3 criteria
Boston, Massachusetts
This trial will test if using a non-invasive brain stimulation technique, called transcranial stimulation, can help people who have trouble understanding speech when multiple people are talking at the same time. They will
Behavioral Intervention
Leadership Program for Mental Health Wellness
Recruiting1 award
Boston, Massachusetts
This trial aims to test a program called LEAP that provides leadership opportunities and mindfulness training to youth of color. The goal is to see if this program can improve civic leadership skills, mental health, and
Total Knee Arthroplasty for Protein-Energy Malnutrition
Recruiting1 award1 criteria
Hartford, Connecticut
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to muscle health (muscle mass, strength, and function) and quality of life in elective orthopedic surgery patients undergoing total joint replacement procedures. Study Aims. Specific aims and their respective approach for the proposed investigation were: Aim 1: Characterize energy status and protein intake in total hip arthroplasty and total knee arthroplasty patients prior to surgery. Approach. Following approval of investigation by the Hartford Hospital Institution Review Board, data collection involved the inclusion of a research information sheet and a 3-day food record with instructions for the respective patient to complete prior to surgery. Aim 2: Evaluate association between energy status, positive or negative energy balance on standard outcome measures assessed throughout physical rehabilitation to determine whether energy status and protein intake at admission predicts objective and subjective rehabilitative outcome measures. Dietary assessments (3-day food record, protein screener) occurred at time points corresponding to physical rehabilitative assessments per approach for Aim 1. Approach. Total Hip Replacement assessments will occur between Day 1 following surgery and Week 2 and 6 months post surgery . Outcome measures included Pain Visual Analog Scale, Hip Disability Osteoarthritis Outcome Score, Timed Up and Go Test, 30 second Sit to Stand Test, Passive Hip Range of Motion and Active Hip Range of Motion. Total knee assessments were taken post surgery on between Day 1 and Week 2 and at 4 to 6 Weeks, and 7 to 12 Weeks following surgery. These included Pain Visual Analog Scale, Knee Injury and Osteoarthritis Outcome Score, Timed Up and Go test, 30-second Sit to Stand Test, Passive and Active Knee Range of Motion, and Knee Strength. Aim 3: Validate a protein screener developed by our research team and designed to characterize protein intake and protein source was administered pre- and post-operatively. For the latter, time points were established according to respective treatment guidelines for Total Hip and Total Knee replacement patients, respectively.
Behavioural Intervention
Conversational Agents for Opioid Use Disorder
Recruiting1 award
Boston, Massachusetts
This trial aims to help people stay in treatment for opioid addiction by using a smartphone app with a virtual character that can have conversations with them. The study wants to see if this virtual character can help patients
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Phase 3 Trials
Corticosteroid
Baxdrostat + Dapagliflozin for Chronic Kidney Disease and High Blood Pressure
Recruiting1 awardPhase 3
East Providence, Rhode Island
This trial will test a new medication called Baxdrostat with Dapagliflozin to see if it can improve kidney health and reduce the risk of heart problems in people with chronic kidney
Aviptidil + SOC for Coronavirus
Recruiting1 awardPhase 3
Boston, Massachusetts
This study looks at the safety and effectiveness of Aviptidil in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with Aviptidil plus current standard of care (SOC), or with placebo plus current SOC.
Remdesivir + SOC for Coronavirus
Recruiting1 awardPhase 3
Boston, Massachusetts
This study looks at the safety and effectiveness of Remdesivir in treating COVID-19 in people who have been hospitalized with the infection and who have acute respiratory failure. Participants in the study will be treated with Remdesivir plus current standard of care (SOC), or with placebo plus current SOC.
Behavioural Intervention
Sleep, Cognition, and Pain Bundle for Delirium
Recruiting2 awardsPhase 3
Boston, Massachusetts
"This trial aims to test a combination of interventions, including improving sleep, cognitive exercises, and extended pain relief after heart surgery to reduce confusion, agitation, and decline in cognitive function. These interventions are based
Trials With No Placebo
Behavioural Intervention
Computerized Decision Support for High Cholesterol
Recruiting1 award1 criteria
Boston, Massachusetts
This trial aims to see if using a computer alert can help doctors identify patients with a genetic high cholesterol condition called Familial Hypercholesterolemia. The main focus is to find out if the
Study 1: Longevity for Intellectual Disability
Recruiting1 award3 criteria
Randolph, Massachusetts
The goal of this clinical trial is to demonstrate feasibility of procedures and compare the outcomes of intervention arrangements to reduce sensory based self-injurious behavior exhibited by individuals with intellectual and developmental disabilities. The main question\[s\] it aims to answer are: (1) Demonstrate ability to meet enrollment requirements. (2) Evaluate acceptability and feasibility of participation relative to observation length and study duration. (3) Track and compare participant progress across interventions. (4) Demonstrate acceptable procedural fidelity and interobserver agreement. And (5) conduct post hoc evaluation of clinical presentation and intervention match. Participants will \[describe the main tasks participants will be asked to do, treatments they'll be given and use bullets if it is more than 2 items\]. If there is a comparison group: Researchers will compare \[insert groups\] to see if \[insert effects\].
Behavioral Intervention
Behavioral Strategies to Improve Sleep for Expectant Mothers
Recruiting1 award5 criteria
Providence, Rhode Island
This trial aims to address the issue of disrupted sleep in pregnant and new mothers, which can have negative effects on their health and their children. Researchers will develop and test a behavioral sleep intervention using short videos
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.