Alfredo Gamboa, MD, MSCI, FAHA ...

Dr. Alfredo Gamboa, MD

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Autonomic Dysfunction Center/ Vanderbilt University Medical Center

Studies Autonomic Failure
Studies Multi-System Atrophy
11 reported clinical trials
23 drugs studied

Affiliated Hospitals

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Autonomic Dysfunction Center/ Vanderbilt University Medical Center

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Vanderbilt University

Clinical Trials Alfredo Gamboa, MD is currently running

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Heating Pad

for High Blood Pressure

Patients with autonomic failure are characterized by disabling orthostatic hypotension (low blood pressure on standing), and at least half of them also have high blood pressure while lying down (supine hypertension). Exposure to heat, such as in hot environments, often worsens their orthostatic hypotension. The causes of this are not fully understood. The purpose of this study is to evaluate whether applying local heat over the abdomen of patients with autonomic failure and supine hypertension during the night would decrease their nocturnal high blood pressure while lying down. This will help us better understand the mechanisms underlying this phenomenon, and may be of use in the treatment of supine hypertension.

Recruiting

0 awards

N/A

2 criteria

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CPAP

for Supine Hypertension

This study aims to learn about the effects of continuous positive airway pressure (CPAP) on people with autonomic failure and high blood pressure when lying down (supine hypertension) to determine if it can be used to treat their high blood pressure during the night. CPAP (a widely used treatment for sleep apnea) involves using a machine that blows air into a tube connected to a mask covering the nose, or nose and mouth, to apply a low air pressure in the airways. The study includes 3-5 days spent in the Vanderbilt Clinical Research Center (CRC): at least one day of screening tests, followed by up to 3 study days. Subjects may be able to participate in daytime and/or overnight studies. The Daytime study consists of 2 study days: one with active CPAP and one with sham CPAP applied for up to 2 hours. The Overnight study consists of 3 study nights: one with active CPAP, one with sham CPAP, both applied for up to 9 hours and one night sleeping with the bed tilted head-up.

Recruiting

0 awards

N/A

4 criteria

More about Alfredo Gamboa, MD

Clinical Trial Related

9 years of experience running clinical trials · Led 11 trials as a Principal Investigator · 9 Active Clinical Trials

Treatments Alfredo Gamboa, MD has experience with

  • Placebo
  • Midodrine
  • Heating Pad
  • Sham Control
  • Angiotensin (1-7)
  • Continuous Positive Airway Pressure (CPAP)

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