Dr. Amit Atrey, MD
Claim this profileSt. Michael's Hospital
Studies Osteoarthritis
Studies Knee Replacement Surgery
5 reported clinical trials
10 drugs studied
Affiliated Hospitals
Clinical Trials Amit Atrey, MD is currently running
CBD
for Persistent Post-Surgical Pain After Knee Replacement
Each year, approximately 75,000 Canadians undergo knee replacement surgery, and up to 25% develop persistent post-surgical pain. Persistent post-surgical pain is associated with depression, anxiety, unemployment, and reduced quality of life. Chronic pain after surgery is often managed with opioid therapy, which typically provides only modest benefits and is associated with rare but serious adverse events, such as overdose and death. A number of studies have found that greater pain just before and after knee replacement surgery is associated with the development of chronic pain, suggesting that reducing peri-operative pain may help prevent persistent post-surgical pain. Medicinal cannabis has begun to emerge as a potential therapy for pain reduction, and produces effects largely due to 2 active components: (1) cannabidiol (CBD), and (2) tetrahydrocannabinol (THC). Studies of CBD have shown analgesic, anti-inflammatory, and anti-anxiety properties, but without the psychoactive effects (feeling 'high') that THC produces. This study will assess the feasibility of a definitive trial to explore whether adding CBD dominant vs. placebo to usual care before and after surgery can reduce the rate of persistent post-surgical pain after total knee replacement. This study will randomize 40 patients to receive either CBD dominant or placebo, and follow them for six months to confirm our ability to recruit patients, adhere to protocol, and capture full outcome data for at least 85% of patients.
Recruiting1 award Phase 34 criteria
Cryoneurolysis
for Knee Pain
This trial is testing a device called Iovera that freezes pain-causing nerves to help people who are having knee replacement surgery. The goal is to reduce pain and the need for opioid medications after surgery. The study will see if this method can make recovery easier and faster.
Recruiting0 awards N/A6 criteria
More about Amit Atrey, MD
Clinical Trial Related4 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Amit Atrey, MD has experience with
- Placebo Oral Capsule
- Cannabinol
- Staged Knee Arthroplasty (UKA)
- Simultaneous Knee Arthroplasty (UKA)
- OR3O™ Dual Mobility System
- Local Anesthetic
Breakdown of trials Amit Atrey, MD has run
Osteoarthritis
Knee Replacement Surgery
Hip Revision Surgery
Hip Osteoarthritis
Chronic Knee Pain
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Amit Atrey, MD specialize in?
Amit Atrey, MD focuses on Osteoarthritis and Knee Replacement Surgery. In particular, much of their work with Osteoarthritis has involved treating patients, or patients who are undergoing treatment.
Is Amit Atrey, MD currently recruiting for clinical trials?
Yes, Amit Atrey, MD is currently recruiting for 2 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Amit Atrey, MD has studied deeply?
Yes, Amit Atrey, MD has studied treatments such as Placebo oral capsule, Cannabinol, Staged Knee Arthroplasty (UKA).
What is the best way to schedule an appointment with Amit Atrey, MD?
Apply for one of the trials that Amit Atrey, MD is conducting.
What is the office address of Amit Atrey, MD?
The office of Amit Atrey, MD is located at: St. Michael's Hospital, Toronto, Ontario M5B 1W8 Canada. This is the address for their practice at the St. Michael's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.