Dr. Sammy Elmariah, MD
Claim this profileMassachusetts General Hospital
Studies Mitral Insufficiency
Studies Mitral Valve Regurgitation
10 reported clinical trials
14 drugs studied
Affiliated Hospitals
Clinical Trials Sammy Elmariah, MD is currently running
Transcatheter Valve Repair
for Mitral Regurgitation
This trial tests a new device called Edwards PASCAL that fixes leaky heart valves without surgery. It is for patients who can't have surgery or haven't improved with other treatments. The device helps the valve close better, stopping blood from leaking backward.
Recruiting1 award N/A9 criteria
Proteomics Analysis
for Heart Valve Disease
The purpose of the HALT Biomarkers study are to identify a panel of circulating proteins that discriminates between patients with and without Hypo-Attenuated Leaflet Thickening (HALT) and can be used to supplement the diagnosis of HALT; to characterize changes in circulating proteins after treatment of HALT with systemic anticoagulation; and to identify circulating proteins that predict the occurrence of HALT. The study population will be adult patients undergoing transfemoral transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS) or bioprosthetic valve degeneration. Enrollment will continue until 30 patients with HALT are identified for completion of phase 1. Based on a HALT incidence rate of 10%, we anticipate enrolling 300 patients. Patients are enrolled prior to undergoing transfemoral TAVR. Blood samples, clinical data and echocardiograms will be collected at the following timepoints: baseline (pre-TAVR, T0), post-TAVR (pre-discharge, T1), 30-day follow-up (window 3-9 weeks, T2), and 6-month follow-up (T3). Cardiac 4D CT will be performed at the 30-day follow-up visit to screen for the occurrence of HALT. Patients with HALT will be treated with systemic anticoagulation for 5-6 months, at which point a follow-up CT scan and blood sample will be obtained. Control subjects will also undergo a 6-month study visit with blood sample collection. The study will be conducted within two phases. Phase 1 will serve as a derivation / discovery study in which candidate protein biomarkers of HALT will be identified. Once this is successfully completed, a second cohort will be enrolled within phase 2. Phase 2 will be performed under the auspices a future contract or amendment and will seek to cross-validate the initial study findings.
Recruiting1 award Phase 13 criteria
More about Sammy Elmariah, MD
Clinical Trial Related6 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Sammy Elmariah, MD has experience with
- Edwards PASCAL System
- Optimal Medical Therapy
- Physician Notification Letter
- Tendyne Mitral Valve System
- MitraClip System
- Abbott Mitraclip System
Breakdown of trials Sammy Elmariah, MD has run
Mitral Insufficiency
Mitral Valve Regurgitation
Tricuspid Regurgitation
Aortic Valve Stenosis
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Sammy Elmariah, MD specialize in?
Sammy Elmariah, MD focuses on Mitral Insufficiency and Mitral Valve Regurgitation. In particular, much of their work with Mitral Insufficiency has involved Stage III patients, or patients who are undergoing treatment.
Is Sammy Elmariah, MD currently recruiting for clinical trials?
Yes, Sammy Elmariah, MD is currently recruiting for 7 clinical trials in Boston Massachusetts. If you're interested in participating, you should apply.
Are there any treatments that Sammy Elmariah, MD has studied deeply?
Yes, Sammy Elmariah, MD has studied treatments such as Edwards PASCAL System, Optimal Medical Therapy, Physician Notification Letter.
What is the best way to schedule an appointment with Sammy Elmariah, MD?
Apply for one of the trials that Sammy Elmariah, MD is conducting.
What is the office address of Sammy Elmariah, MD?
The office of Sammy Elmariah, MD is located at: Massachusetts General Hospital, Boston, Massachusetts 02114 United States. This is the address for their practice at the Massachusetts General Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.