Dr. Veronique Brulotte, MD, MSc
Claim this profileMaisonneuve-Rosemont Hospital
Studies Chronic Pain
Studies Postoperative Pain
3 reported clinical trials
3 drugs studied
Affiliated Hospitals
Clinical Trials Veronique Brulotte, MD, MSc is currently running
Epidural Pain Management
for Postoperative Pain
Pain control after surgery is a crucial component of postoperative recovery. Thus, in open abdominal surgery, the use of TEA (Thoracic epidural analgesia) has become a gold standard. However, analgesia may still remain a challenge, especially in patients with large incision abdominal incisions. To address this problem, the use of the PIEB (Programmed intermittent epidural bolus) mode has been proposed, because it offers a better spread of the epidural medication. Only a few studies have evaluated the superiority of this PIEB mode in open abdominal surgery, yielding conflicting results. However, PIEB showed to be at least as effective in controlling pain as CEI, and clinical experience shows that it can be a valuable tool, especially in patients with a large laparotomy incision. However, the optimal dosage of the PIEB mode has never been determined, Furthermore, it is known whether men and women have the same dosage needs to achieve adequate analgesia since most studies have failed to account for sex-based differences in postoperative analgesia. Hence, the main objective of this study will be to determine the optimal volume dose of the PIEB delivered at a fixed interval of 60 min in patients undergoing surgery using a large midline laparotomy incision. The optimal dose for male and female patients will be determined separately by evaluating men and women in two independent groups. We hypothesize that the optimal dose of the PIEB that will provide effective analgesia in 90% of patients on the first postoperative day will range between 5 and 10 mL, for both groups. The primary outcome in both groups is successful analgesia. It is defined as a requirement of 5 or less patient-controlled epidural boluses between 8 AM and 8 PM on the first postoperative day. Secondary outcomes will be the incidence of motor block and hypotension, comparison of the level of sensory block according to group, comparison of patient satisfaction according to group and comparison of Quality of Recovery-15 score at 48h post-op according to group.
Recruiting1 award N/A2 criteria
Dexamethasone
for Chronic Pain After Thoracic Surgery
Post thoracotomy pain syndrome still affects 50% of patients after a thoracic surgery. Pathogenesis is unclear but there is growing evidence that neuro inflammation may play a significant role. Dexamethasone is a very potent anti-inflammatory drug. The hypothesis of this study is that dexamethasone, given pre operatively, would help reduce the incidence of post thoracotomy pain syndrome 3 months after surgery, by reducing the inflammatory response, in patients undergoing elective thoracic surgery that includes thoracic epidural analgesia.
Recruiting2 awards N/A3 criteria
More about Veronique Brulotte, MD, MSc
Clinical Trial Related1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Veronique Brulotte, MD, MSc has experience with
- Programmed Intermittent Epidural Bolus
- Dexamethasone
- Palisade Sacroiliac Joint Radiofrequency Ablation Using 3-tined Needles
Breakdown of trials Veronique Brulotte, MD, MSc has run
Chronic Pain
Postoperative Pain
Epidural Analgesia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Veronique Brulotte, MD, MSc specialize in?
Veronique Brulotte, MD, MSc focuses on Chronic Pain and Postoperative Pain. In particular, much of their work with Chronic Pain has involved treating patients, or patients who are undergoing treatment.
Is Veronique Brulotte, MD, MSc currently recruiting for clinical trials?
Yes, Veronique Brulotte, MD, MSc is currently recruiting for 2 clinical trials in Montréal Quebec. If you're interested in participating, you should apply.
Are there any treatments that Veronique Brulotte, MD, MSc has studied deeply?
Yes, Veronique Brulotte, MD, MSc has studied treatments such as Programmed intermittent epidural bolus, Dexamethasone, Palisade sacroiliac joint radiofrequency ablation using 3-tined needles.
What is the best way to schedule an appointment with Veronique Brulotte, MD, MSc?
Apply for one of the trials that Veronique Brulotte, MD, MSc is conducting.
What is the office address of Veronique Brulotte, MD, MSc?
The office of Veronique Brulotte, MD, MSc is located at: Maisonneuve-Rosemont Hospital, Montréal, Quebec H1T2m4 Canada. This is the address for their practice at the Maisonneuve-Rosemont Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.