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Monoclonal Antibodies

Quarterly Ranibizumab 0.5mg for Age-Related Macular Degeneration (PREVENT Trial)

Phase 1 & 2
Waitlist Available
Led By Maziar Lalezary, MD
Research Sponsored by Southern California Desert Retina Consultants, MC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Summary

This study will determine whether quarterly injections of Ranibizumab may prevent eyes with dry age-related macular degeneration from progressing to wet age-related macular degeneration (AMD).

Eligible Conditions
  • Age-Related Macular Degeneration

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Development of exudative AMD
Secondary study objectives
Baseline predictive factors
Development of geographic atrophy (GA)
Number of injections
+4 more

Trial Design

2Treatment groups
Active Control
Group I: Quarterly Ranibizumab 0.5mgActive Control1 Intervention
Quarterly intravitreal injection of 0.5mg ranibizumab
Group II: ShamActive Control1 Intervention
Sham Injection

Find a Location

Who is running the clinical trial?

Southern California Desert Retina Consultants, MCLead Sponsor
1 Previous Clinical Trials
40 Total Patients Enrolled
Maziar Lalezary, MDPrincipal InvestigatorSouthern California Desert Retina Consultants
1 Previous Clinical Trials
45 Total Patients Enrolled
~10 spots leftby Sep 2025