Multidisciplinary Team Care for Breast Cancer
(TITAN Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Waitlist Available

Sponsor: University of Alberta

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?

People with breast cancer often experience many short and long-term side effects as a result of both the cancer and the necessary treatments. Receiving extra assessments and care from teams of multiple health professionals has been shown to be helpful for people with other health problems, such as heart disease. These 'multidisciplinary' teams may include nurses, doctors, pharmacists, dietitians, exercise therapists, counselors, and other specialists. Currently, the investigators do not know if receiving extra assessments from a multidisciplinary team is helpful for people receiving cancer treatment. In this study, the investigators hope to learn the effect of extra assessments and early interventions from teams of health care professionals in people diagnosed with cancer, during and after the treatment period. After initial assessments, participants will be randomized to multidisciplinary team intervention or usual care.

Research Team

Eligibility Criteria

This trial is for adults over 18 with breast cancer or lymphoma, scheduled for specific chemotherapy treatments, and able to attend follow-ups. It's not for those with heart issues, prior thorax radiotherapy, previous similar chemo treatments, physical disability impeding certain tests, psychiatric conditions affecting consent, or involvement in related studies.

Inclusion Criteria

willing to attend follow-up visits.

My cancer (breast or lymphoma) has been confirmed through tissue examination.

I am scheduled for chemotherapy that includes anthracycline or trastuzumab.

See 1 more

Exclusion Criteria

I have had radiation therapy to my chest area before.

I have had treatments with anthracycline or trastuzumab.

I do not have heart failure, cardiomyopathy, or an LVEF below 50%.

See 3 more

Treatment Details

Interventions

Multidisciplinary team intervention (Behavioral Intervention)

Trial OverviewThe TITAN Study is testing whether extra care from a team of various health professionals (like nurses and dietitians) can benefit people with cancer during and after treatment. Participants will be randomly assigned to receive either this multidisciplinary intervention or the usual care.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: multidisciplinary team interventionExperimental Treatment1 Intervention

Intervention arm receives regular assessments and treatments from cardiology team, clinical nutrition, pharmacist, exercise physiologist and physiotherapist

Group II: Observational armActive Control1 Intervention

Participants randomized to observational arm will receive usual care.