PF-06823859 for Myositis
Trial Summary
What is the purpose of this trial?
This trial is testing a new medicine called PF-06823859 for adults with muscle inflammation diseases DM and PM. The goal is to see if it can safely reduce muscle inflammation and weakness.
Will I have to stop taking my current medications?
The trial requires participants to be on a stable dose of their current corticosteroid or immunosuppressant medication. The protocol does not specify if other medications need to be stopped, but it seems you can continue your current treatment if it meets the study's criteria.
What makes the drug PF-06823859 unique for treating myositis?
PF-06823859, also known as Dazukibart, is a novel treatment for myositis, a condition with limited standard treatment options. Its uniqueness may lie in its specific mechanism of action or formulation, which is not detailed in the available research, but it is being compared to a placebo in clinical trials to assess its effectiveness.12345
Research Team
Pfizer CT.gov Call Center
Principal Investigator
Pfizer
Eligibility Criteria
This trial is for adults over 18 with active Dermatomyositis (DM) or Polymyositis (PM), who are on a stable dose of corticosteroids or immunosuppressants. It's not suitable for those not meeting the specific disease criteria or unable to follow the study protocol.Inclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive PF-06823859 or placebo via intravenous infusion every 4 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- PF-06823859 (Monoclonal Antibodies)
- Placebo (Other)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Pfizer
Lead Sponsor