Dietary Sodium Restriction for Salt Sensitivity

Recruiting in Palo Alto (17 mi)

Overseen by David G Edwards, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Waitlist Available

Sponsor: University of Delaware

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine the effects of dietary salt restriction on central hemodynamics and vascular function in men and women with salt resistant blood pressure.

Eligibility Criteria

This trial is for men and women who typically eat more than 3400mg of sodium daily and have normal blood pressure that doesn't change much with salt intake. They must be able to consent, have a normal ECG, blood tests, not be on blood pressure meds or pregnant, not obese, and free from heart disease, cancer, diabetes or kidney issues.

Inclusion Criteria

You regularly consume more than 3400mg of sodium per day in your diet.

Exclusion Criteria

Current abnormal blood panel (assessed by comprehensive metabolic panel, lipid panel and complete blood count).

I am unable to give my consent.

Abnormal resting ECG

Treatment Details

Interventions

• Control (Other)
• Dietary Sodium Restriction (Other)

Trial Overview The study aims to see how eating less salt affects the body's central hemodynamics (how the heart pumps blood) and vascular function (how the blood vessels work). Participants will follow a low-sodium diet compared to their usual high intake.

Participant Groups

Group I: Dietary Sodium Restriction Experimental Treatment 1 Intervention

Daily habitual dietary sodium intake \< 2000mg

Group II: Control Placebo Group 1 Intervention

Routine habitual dietary sodium intake \>3400mg

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

Department of Kinesiology and Applied Physiology, University of Delaware Newark, DE

Who Is Running the Clinical Trial?

University of Delaware Lead Sponsor

References