Flu Vaccine for Melanoma Patients

Recruiting in Palo Alto (17 mi)

Overseen byE. John Wherry, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Waitlist Available

Sponsor: University of Pennsylvania

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?

Influenza vaccination is indicated for all adults, but the immunogenicity of vaccination has not been assessed in all situations. We are conducting a prospective unblinded study of influenza vaccine recipients.

Research Team

E. John Wherry, PhD

Principal Investigator

University of Pennsyvlania

Eligibility Criteria

This trial is for adults who can consent and have advanced or metastatic melanoma. They shouldn't be allergic to flu vaccines, haven't had a flu shot in the last 6 months, aren't on strong immune system-suppressing drugs, don't have HIV, haven’t had an organ or bone marrow transplant, and aren't in other blood-drawing studies.

Inclusion Criteria

My melanoma has spread beyond its original site.

I am an adult who can legally consent.

Exclusion Criteria

You are participating in other studies that require a lot of blood to be drawn during the same time as this study.

You are allergic to the flu vaccine.

I have had a solid organ or bone marrow transplant.

See 4 more

Treatment Details

Interventions

Inactivated Influenza Vaccine (Vaccine)

Trial OverviewThe study is testing how well the inactivated influenza vaccine works for people with melanoma. It's a prospective study where participants know they're getting the flu vaccine to see their body's response to it.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Influenza vaccination cohortExperimental Treatment1 Intervention

Subjects will receive one dose of seasonal quadrivalent inactivated influenza vaccine intramuscularly for standard of care for prevention of influenza infection.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials

2,118

Recruited

45,270,000+

Dr. Joan Lau

University of Pennsylvania

Chief Executive Officer since 2020

PhD in Neuroscience from the University of Cincinnati College of Medicine, MBA from the Wharton School of Business, BS in Bioengineering from the University of Pennsylvania