~36 spots leftby Apr 2026

Multicenter Infection Surveillance Study Following Open Heart Surgery

Recruiting in Palo Alto (17 mi)
+7 other locations
AH
Overseen byAli Husain, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 4
Waitlist Available
Sponsor: Halyard Health
No Placebo Group
Prior Safety Data

Trial Summary

What is the purpose of this trial?

The main goals of the study are as follows: (1) to determine the correlation between pain management using continuous infusion of local anesthetics and the incidence of pneumonia and surgical infection in cardiac surgery patients; and (2) to evaluate the relationship between hospital-acquired pneumonia and surgical infection and patient outcomes, including length of hospital stay.

Research Team

AH

Ali Husain, MD

Principal Investigator

The Cleveland Clinic

Eligibility Criteria

Inclusion Criteria

Scheduled for elective cardiac surgical procedure, including coronary revasculari-zation or valve surgery;
Provision of informed consent
Men and women, >18 years of age;

Treatment Details

Interventions

  • Continuous Infusion of Local Anesthetics (Local Anesthetic)
  • Continuous Sternal Block (Device)
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Continuous Sternal BlockExperimental Treatment1 Intervention
Continuous Sternal block with infusion of local anesthetic via ON-Q Painbuster Silver Soaker system
Group II: Opioid based analgesiaActive Control1 Intervention
Opioid based analgesia including Patient controlled analgesia plus IM, Oral narcotics and other analgesics

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Waukesha Medical CenterWest Allis, WI
University of Kentucky Medical CenterLexington, KY
Methodist HospitalHouston, TX
St. Vincents EastBirmingham, AL
More Trial Locations
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Who Is Running the Clinical Trial?

Halyard Health

Lead Sponsor

Trials
17
Patients Recruited
4,000+