PAP Treatment for Sleep Apnea with PTSD and Substance Use Disorders

N/A

Recruiting

Led By Peter Colvonen, PhD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Capable of giving informed consent

At least 18 years of age

Must not have

Central sleep apnea (AHI >=5 and > 50% central apneas)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, post-sarrtp unit (28 days), 3-month follow up (90 days)

Awards & highlights

No Placebo-Only Group

Summary

This trial is comparing the effects of treating obstructive sleep apnea in veterans with substance use disorder and posttraumatic stress disorder who are living in a residential setting. The investigators hypothesis is that treating OSA will have better functional, SUD, and PTSD outcomes.

Who is the study for?

This trial is for U.S. Veterans or Reserve/National Guard members who are at least 18 years old, have PTSD and SUD, can read English, and are in a residential treatment program. They must have experienced trauma and used substances for at least 20 days in the last three months. Those with severe cognitive issues, central sleep apnea, psychosis outside of substance use, or already using PAP devices cannot join.

What is being tested?

The study tests if using a Positive Airway Pressure (PAP) device to treat Obstructive Sleep Apnea (OSA) improves overall function, PTSD symptoms, and substance use outcomes better than waiting for treatment among veterans with both SUD/PTSD in residential care.

What are the potential side effects?

While not explicitly stated here, common side effects of using PAP devices may include discomfort or irritation from the mask interface, dry nose or throat sensation due to airflow pressure changes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I understand the study and can agree to participate.

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I am 18 years old or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have central sleep apnea with more than half of my breathing interruptions being central in nature.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, post-sarrtp unit (28 days), 3-month follow up (90 days)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, post-sarrtp unit (28 days), 3-month follow up (90 days)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-sarrtp unit (28 days), 3-month follow up (90 days) for reporting.