Whey Protein for Metabolic Bone Health
(BonePRO Trial)

Recruiting in Palo Alto (17 mi)

Overseen byJenna Gibbs, PhD

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: McGill University

No Placebo Group

Trial Summary

What is the purpose of this trial?The goal of this clinical trial is to investigate the effects of protein ingestion post-exercise on bone turnover markers. The main questions it aims to answer is: Does protein ingestion independently influence the bone metabolic response to exercise in endurance runners? We will compare dietary protein to a placebo (water) to detect changes in bone turnover markers. Participants will: In a within-subject design, participants will perform an exhaustive run and take either protein or placebo immediately post-exercise. Track physical activity and diet before each arm of the intervention and during the washout period.

Eligibility Criteria

This trial is for endurance runners who are interested in how protein affects their bone health after exercise. Participants should be healthy, with no metabolic bone diseases or conditions affecting metabolism. They must track their diet and activity, and not take other supplements that could influence the results.

Inclusion Criteria

Competitive runner for at least one season (minimum 40 km/week for the past 6-months)

I am between 18 and 35 years old.

My BMI is within the healthy range of 18.5 to 24.9.

+1 more

Exclusion Criteria

My condition or medication affects my bone health.

I have been diagnosed with an eating disorder.

I do not have uncontrolled thyroid, digestive, or bone diseases.

+5 more

Participant Groups

The study tests if drinking whey protein right after running changes markers in the blood that show bone turnover compared to just drinking water. Runners will do an exhaustive run twice: once they'll have protein afterwards, and another time they'll have a placebo.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Whey Protein BeverageExperimental Treatment1 Intervention

Chocolate flavoured whey protein supplement as a post-exercise recovery beverage. One beverage post-exercise. Dose based on participant body weight.

Group II: Control BeveragePlacebo Group1 Intervention

Water beverage with calorie-free chocolate syrup as a post-exercise recovery beverage. Isovolumetric.