Trial Summary
What is the purpose of this trial?This trial studies how an investigational surgical procedure called vascularized lymph node transfer works in lowering the risk of arm swelling (lymphedema) in patients with breast cancer undergoing breast reconstruction. Patients who undergo breast reconstruction are often at high risk of developing lymphedema. Vascularized lymph node transfer involves transferring lymph nodes from an unaffected area of the body to replace those removed as part of treatment, which may lower the risk of lymphedema after breast reconstruction.
Eligibility Criteria
This trial is for breast cancer patients who've had a mastectomy, lymph node removal, radiation, and chemotherapy and are now planning breast reconstruction. It's not for those pregnant or allergic to specific dyes used during surgery.Inclusion Criteria
I have completed treatment for breast cancer and am seeking breast reconstruction.
Exclusion Criteria
Patients that are known to be pregnant at the time of surgery
You are allergic to indocyanine green (ICG) or isosulfan blue (Lymphazurin).
Participant Groups
The study tests a new surgical method called vascularized lymph node transfer alongside breast reconstruction to see if it can reduce the risk of developing arm swelling (lymphedema) after surgery.
1Treatment groups
Experimental Treatment
Group I: Treatment (vascularized lymph node transfer)Experimental Treatment2 Interventions
Patients undergo vascularized lymph node transfer during standard of care breast reconstructive surgery.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
M D Anderson Cancer CenterHouston, TX
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Who Is Running the Clinical Trial?
M.D. Anderson Cancer CenterLead Sponsor
National Cancer Institute (NCI)Collaborator