~4 spots leftby Jul 2025

TMS for Autism Spectrum Disorder

(TMSinASD Trial)

Recruiting in Palo Alto (17 mi)
Age: 18 - 65
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Yale University
Approved in 3 jurisdictions

Trial Summary

What is the purpose of this trial?This trial will test if using magnetic pulses can improve social skills in adults with Autism Spectrum Disorder (ASD). The study will measure brain and behavior changes over time. Magnetic stimulation has been explored in various studies as a potential treatment for autism spectrum disorder (ASD), showing positive behavioral and brain activity results.

Eligibility Criteria

This trial is for individuals aged 18-40 with either typical development or a diagnosis of Autism Spectrum Disorder (ASD). They must be able to undergo EEG and eye-tracking tests. It's not suitable for those with serious brain issues, major psychiatric illnesses, medical conditions like stroke or seizures, recent drug/alcohol use, pregnant women, or anyone with metal in their body.

Inclusion Criteria

I am between 18 and 40 years old and either typically developing or have autism.
You are able to take part in a test that involves an EEG (a brain activity measurement) and eye-tracking.

Exclusion Criteria

Participants with major psychiatric illness that would preclude completion of study measures
You have consumed alcohol or used recreational drugs within the past day.
I am not pregnant nor suspect I might be.
+4 more

Participant Groups

The study is testing the impact of repetitive Transcranial Magnetic Stimulation (rTMS) on how people with ASD process social information. This involves looking at changes in brain activity and behavior before and after TMS using EEGs and eye-tracking technology.
2Treatment groups
Active Control
Placebo Group
Group I: Transcranial Magnetic Stimulation - realActive Control1 Intervention
Participants will receive active TMS during their study visit
Group II: Transcranial Magnetic Stimulation - shamPlacebo Group1 Intervention
Participants will receive sham stimulation during their study visit simulating TMS

TMS is already approved in United States, European Union, Canada for the following indications:

πŸ‡ΊπŸ‡Έ Approved in United States as Transcranial Magnetic Stimulation for:
  • Depression
  • Anxiety disorders
  • Post-traumatic stress disorder (PTSD)
  • Obsessive-compulsive disorder (OCD)
πŸ‡ͺπŸ‡Ί Approved in European Union as Transcranial Magnetic Stimulation for:
  • Depression
  • Anxiety disorders
  • Post-traumatic stress disorder (PTSD)
  • Obsessive-compulsive disorder (OCD)
πŸ‡¨πŸ‡¦ Approved in Canada as Transcranial Magnetic Stimulation for:
  • Depression
  • Anxiety disorders
  • Post-traumatic stress disorder (PTSD)
  • Obsessive-compulsive disorder (OCD)

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Yale UniversityNew Haven, CT
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Who Is Running the Clinical Trial?

Yale UniversityLead Sponsor

References