Voice Quality Analysis for Tracheal Stenosis

Overseen By Samuel L Collins, Ph.D.

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Johns Hopkins University

Disqualifiers: Laryngeal disease, Neurological disease, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if changes in voice can predict when a person with Laryngotracheal Stenosis (a narrowing of the windpipe) might need a procedure to widen it. Researchers believe that regular voice recordings analyzed with artificial intelligence could serve as a useful tool. The trial includes individuals diagnosed with Laryngotracheal Stenosis who can use a smartphone app for the study. As an unphased trial, it offers participants the chance to contribute to innovative research that could lead to new, non-invasive monitoring techniques.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to analyze voice quality in patients with laryngotracheal stenosis, offering a new way to assess how treatments impact their voice. Unlike traditional methods, which may focus more on physical symptoms and airway function, this approach prioritizes the patient's vocal experience. By understanding the nuances of voice changes, researchers hope to refine treatment strategies and improve overall quality of life for patients, making this investigation a promising step forward in personalized care.

Who Is on the Research Team?

Alexander Hillel, MD

Principal Investigator

Johns Hopkins School of Medicine

Are You a Good Fit for This Trial?

Inclusion Criteria

You need to understand the information about the study and give permission by signing a form.

You need to have records showing when you were diagnosed with laryngotracheal stenosis and details about any previous treatments or surgeries.

You currently have a diagnosis of a narrowed airway in your throat.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Initial voice quality and other health metrics are assessed using VoiceLab automated voice analysis software and other tools

2 weeks

1 visit (virtual)

Remote Monitoring

Participants' voice quality is remotely monitored using regular voice recordings to predict the need for dilation procedures

2 years

Monthly virtual assessments

Follow-up

Participants are monitored for safety and effectiveness after the main monitoring period

4 weeks

What Are the Treatments Tested in This Trial?

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials

2,366

Recruited

15,160,000+