IPD Probe for Gut Permeability

Recruiting in Palo Alto (17 mi)

Overseen byGuillermo Tearney, M.D, PhD.

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Massachusetts General Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability

Eligibility Criteria

This trial is for healthy adults aged 18-60 who can consent and fast for at least 8 hours. It's not suitable for those with respiratory diseases, nasal steroid use, gastric emptying delays, alcoholism, certain medication uses (like clotting impairments or mast cell stabilizers), recent antibiotics use, liver diseases, galactosemia, uncontrolled diabetes, lactation due to pregnancy or any contraindications to nasopharyngeal procedures.

Inclusion Criteria

Subject must fast (no solid food) for at least 8 hours prior to the procedure

I can understand and agree to the treatment plan.

I am between 18 and 60 years old.

+1 more

Exclusion Criteria

I have been diagnosed with or suspected to have Galactosemia.

I am on medication that slows down my stomach emptying.

I am currently taking medication for heartburn or ulcers.

+14 more

Participant Groups

The study is testing the feasibility of a trans-nasal IPD probe as a tool to measure gut permeability. Participants will undergo this minimally invasive procedure where the probe is inserted through the nose to assess intestinal function.

1Treatment groups

Experimental Treatment

Group I: Feasibility of trans-nasal IPD probeExperimental Treatment1 Intervention

The purpose of this study is to examine the feasibility of using a trans-nasal IPD probe as a measurement tool for gut permeability