← Back to Search

Behavioral Intervention

Deprexis for Depression (Deprexis Trial)

N/A
Recruiting
Led By Rahel R Pearson, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, post-treatment (week 8), follow-up (week 16)
Awards & highlights

Summary

This trial will examine the effectiveness of an online program called Deprexis in helping Veterans with mild to moderate depressive symptoms. The program will be compared to standard treatment to see if it is helpful. The

Who is the study for?
This trial is for Veterans experiencing mild to moderate depression. Participants should be interested in a self-guided, internet-based intervention and available for an 8-week course. Specific eligibility criteria are not provided, but typically participants would need access to the internet and have no conditions that significantly interfere with study participation.
What is being tested?
The trial tests Deprexis, an online program designed to help manage depressive symptoms. Veterans will either use Deprexis or receive their usual treatment over eight weeks. The goal is to see if Deprexis can improve mental health outcomes and daily functioning more than standard treatments.
What are the potential side effects?
Since Deprexis is a non-medical, computerized intervention focusing on mental health therapy, it may not have traditional side effects like medications do. However, users might experience emotional discomfort or distress as they address their depressive symptoms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, post-treatment (week 8), follow-up (week 16)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-treatment (week 8), follow-up (week 16) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Quick Inventory of Depressive Symptomatology (Self-Report; QIDS-SR-16) Change
The Sheehan Disability Scale (SDS) Change
World Health Organization Disability Assessment Schedule-II (WHODAS) Change

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: DeprexisExperimental Treatment1 Intervention
Deprexis: an internet-delivered psychosocial treatment for depressive symptoms and related functional impairment.
Group II: Treatment-as-UsualActive Control1 Intervention
Access to standard non-study care
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Deprexis
2013
N/A
~1640

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,647 Previous Clinical Trials
3,359,918 Total Patients Enrolled
78 Trials studying Depression
19,792 Patients Enrolled for Depression
Rahel R Pearson, PhDPrincipal InvestigatorCentral Texas Veterans Health Care System Waco VA Medical Center, Waco, TX
~101 spots leftby Apr 2029
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top