Heart Rate Variability in Depression

Recruiting in Palo Alto (17 mi)

+2 other locations

Overseen byAndrea Crowell, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Emory University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to understand if there is a relationship between the way that emotions are regulated by the brain and the way that heart rate is regulated by the brain. The study also seeks to understand whether having depression changes the way that emotions and heart rate are regulated.

Research Team

Andrea Crowell, MD

Principal Investigator

Emory University

Eligibility Criteria

Inclusion Criteria

Ages 18-65 years

Able to understand and provide informed consent

Male and female

See 3 more

Treatment Details

Interventions

Imaginal Task (Behavioral Intervention)
Video Task (Behavioral Intervention)

Participant Groups

2Treatment groups

Experimental Treatment

Group I: Healthy ControlsExperimental Treatment2 Interventions

Healthy controls will complete the video task and imaginal task in one session

Group II: Depressed + KetamineExperimental Treatment2 Interventions

Subjects with major depressive disorder (MDD) who are scheduled to receive ketamine infusions will complete the video task and imaginal task twice. The first visit will be before any ketamine treatment. The second visit will be within 1 week after first ketamine infusion. This is NOT at treatment study. Study inclusion is open to participants with MDD who are already planning to receive ketamine treatment at Emory. No treatment is offered through this study.