~78 spots leftby Apr 2026

Patient Activation Program + Text Messaging for Type 2 Diabetes

Recruiting in Palo Alto (17 mi)
AO
Overseen byAdesuwa Olomu, MD, MS
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: Michigan State University
Must be taking: Blood pressure, cholesterol
Disqualifiers: Cognitive impairment, dementia, psychosis, others
No Placebo Group

Trial Summary

What is the purpose of this trial?

Cardiovascular disease (CVD) complications are the leading cause of diabetes mellitus (DM)-related morbidity and mortality, creating a significant burden on the public health system. This burden is, in part, attributable to poor medication adherence, with 21-42% of patients failing to properly adhere to their care. Importantly, this issue is especially pronounced in minority and low-income populations, which show higher rates of chronic illness and lower medication adherence. Interventions that foster and reinforce patient-centered communication between clinicians and patients show promise in improving health outcomes. However, they have not been widely implemented, in part due to a lack of compelling evidence for their effectiveness in primary care settings. Project Objective: The investigators propose to evaluate the impact of a patient activation program: Office Guidelines Applied to Practice (Office-GAP) combined with mobile text messaging reinforcement (Way to Health \[W2H\]) on medication adherence in patients with DM compared to mobile texting alone. Office-GAP incorporates shared decision-making and a decision/support checklist to be completed during office visits, to foster patients' investment in their own care. W2H is a texting service that informs and encourages patients to adhere to goals and improve communication. The long-term goal is to develop a model that can reliably improve and sustain adherence and can be successfully implemented in primary care clinics to close the morbidity and mortality gap for minority/low-income DM patients. The hypothesis is that the combined face-to-face patient activation and texting- delivered reinforcement methods will facilitate communication between patients and providers, improving the frequency, accuracy, and timeliness of communication while reinforcing shared goals and engendering mutual respect more than texting alone. Improved communication between patients and providers may improve medication adherence, blood sugar, cholesterol, blood pressure control, and patient satisfaction with providers, and ultimately decrease burden of illness. Research Strategy: The investigators will conduct a randomized community-based clinical trial in Federally-Qualified Health Centers (FQHCs) in Michigan enrolling 378 patients in 17 teams. All patients will receive usual care and medication for DM and CVD prevention. Eight teams will use W2H alone, and 9 teams will combine Office-GAP with WTH. The investigators will evaluate the impact of shared decision-making strategies for patients and providers. Impact: If successfully translated to clinical practice, these interventions have the potential to significantly impact patient care in FQHCs, improving outcomes for DM and CVD. This research also paves the way for shifting clinical practice across a spectrum of chronic disease where medication non-adherence is an issue.

Will I have to stop taking my current medications?

The trial does not specify that you need to stop taking your current medications. In fact, all patients will continue to receive their usual care and medication for diabetes and cardiovascular disease prevention.

What data supports the effectiveness of the treatment Mobile text messaging, Office Guidelines Applied to Practice (Office-GAP) + Mobile text messaging, Office-GAP + W2H, Office Guidelines Applied to Practice + Mobile Text Messaging for Type 2 Diabetes?

Research shows that text messaging can help people with type 2 diabetes manage their condition by providing reminders and motivation for self-care activities, like physical activity and healthy eating. While the exact combination of treatments in the trial hasn't been directly studied, similar text messaging programs have been found to improve health outcomes and patient satisfaction.12345

Is text messaging for diabetes management safe for humans?

Research shows that using text messages for diabetes management is generally safe, with no reports of harmful effects like misreading data or privacy issues. However, more personalized messages may be needed to better meet individual needs.56789

How is the Patient Activation Program + Text Messaging treatment for Type 2 Diabetes different from other treatments?

This treatment is unique because it combines a patient activation program with mobile text messaging to support self-management of Type 2 Diabetes, offering personalized behavioral coaching, education, and reminders through a convenient and low-cost platform.148910

Research Team

AO

Adesuwa Olomu, MD, MS

Principal Investigator

Michigan State University

Eligibility Criteria

This trial is for adults over 18 with Type 2 diabetes and HbA1c >8, who are taking medication for blood pressure or cholesterol. They must be able to consent, have a cell phone (provided if needed), and read/speak English at a grade 6 level. It excludes those planning to move away, with cognitive impairments or in another cellphone program.

Inclusion Criteria

Patients must be able to read and speak English (grade 6 reading level)
I am on medication for blood pressure or cholesterol.
I am over 18, have Type 2 diabetes with HbA1c over 8, and may or may not have heart disease.
See 2 more

Exclusion Criteria

Plans to leave the area prior to study completion
Participating in another cellphone program
You have a medical record showing problems with memory, thinking, or mental health.

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive either Office-GAP + mobile phone text messaging or mobile phone text messaging alone

12 months
1 group visit, follow-up visits at 0-1, 3, 6, 9, and 12 months

Follow-up

Participants are monitored for medication adherence and health outcomes

3 months

Treatment Details

Interventions

  • Mobile text messaging (Behavioral Intervention)
  • Office Guidelines Applied to Practice (Office-GAP) + Mobile text messaging (Behavioral Intervention)
Trial OverviewThe study tests the Office-GAP program plus mobile texting against mobile texting alone in improving medication adherence among diabetic patients. Office-GAP involves shared decision-making during visits; both groups receive usual care and texts encouraging adherence.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Office Guidelines Applied to Practice (Office-GAP) + mobile phone text messagingExperimental Treatment1 Intervention
Participants receive Office Guidelines Applied to Practice (Office-GAP) + mobile phone text messaging for 12 months.
Group II: Mobile phone text messagingActive Control1 Intervention
Participants receive mobile phone text messaging alone for 12 months.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Michigan State University

Lead Sponsor

Trials
202
Recruited
687,000+
Doug Gage profile image

Doug Gage

Michigan State University

Chief Executive Officer

PhD in Botany from the University of Texas

David Smith profile image

David Smith

Michigan State University

Chief Medical Officer

MD from Michigan State University

University of Michigan

Collaborator

Trials
1,891
Recruited
6,458,000+

Marschall S. Runge

University of Michigan

Chief Executive Officer since 2015

MD, PhD

Karen McConnell profile image

Karen McConnell

University of Michigan

Chief Medical Officer since 2020

MD

Findings from Research

The study involved 126 patients with type 2 diabetes mellitus over a 6-month period, showing that personalized text messages significantly increased physical activity in the intervention group during the third and fourth months compared to the control group.
While the intervention group did not show a statistically significant difference in overall monthly step counts compared to the control group over the entire study, they did achieve a meaningful reduction in HbA1c levels from baseline, indicating potential benefits in diabetes management.
Text to Move: A Randomized Controlled Trial of a Text-Messaging Program to Improve Physical Activity Behaviors in Patients With Type 2 Diabetes Mellitus.Agboola, S., Jethwani, K., Lopez, L., et al.[2022]
A systematic review of 151 studies found that mobile text messaging interventions had no statistically significant effect on increasing physical activity in people with type 2 diabetes mellitus, based on a meta-analysis of 5 studies (P=0.16).
The review also indicated that text messaging did not significantly impact glycemic control or anthropometric measures like weight and BMI, highlighting the need for more high-quality research in this area.
The Effectiveness of Mobile Phone Messaging-Based Interventions to Promote Physical Activity in Type 2 Diabetes Mellitus: Systematic Review and Meta-analysis.Alsahli, M., Abd-Alrazaq, A., Househ, M., et al.[2022]
In a study involving 69 adults with uncontrolled type 2 diabetes, sending automated SMS messages promoting diabetes self-care led to a significant reduction in hemoglobin A1c (HbA1c) levels by an average of 0.97%, indicating improved glycemic control.
The study suggests that non-tailored SMS messages can be an effective addition to standard care for managing poorly controlled diabetes, but further research with larger sample sizes and longer durations is needed to explore the full potential of this intervention.
Impact of Non-Tailored One-Way Automated Short Messaging Service (OASMS) on Glycemic Control in Type 2 Diabetes: A Retrospective Feasibility Study.Alamer, A., Palm, C., Almulhim, AS., et al.[2022]

References

Going mobile with diabetes support: a randomized study of a text message-based personalized behavioral intervention for type 2 diabetes self-care. [2022]
Healthcare via cell phones: a systematic review. [2022]
Text to Move: A Randomized Controlled Trial of a Text-Messaging Program to Improve Physical Activity Behaviors in Patients With Type 2 Diabetes Mellitus. [2022]
The Effectiveness of Mobile Phone Messaging-Based Interventions to Promote Physical Activity in Type 2 Diabetes Mellitus: Systematic Review and Meta-analysis. [2022]
Text messaging intervention for teens and young adults with diabetes. [2021]
Impact of Non-Tailored One-Way Automated Short Messaging Service (OASMS) on Glycemic Control in Type 2 Diabetes: A Retrospective Feasibility Study. [2022]
A Research Protocol to Test the Effectiveness of Text Messaging and Reminder Calls to Increase Service Use Referrals in a Community Engagement Program. [2020]
Computerized Automated Reminder Diabetes System (CARDS): e-mail and SMS cell phone text messaging reminders to support diabetes management. [2022]
Diabetes Text-Message Self-Management Support Program (SMS4BG): A Pilot Study. [2018]
Patient Perspectives on a Targeted Text Messaging Campaign to Encourage Screening for Diabetes: Qualitative Study. [2023]