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Behavioural Intervention

Exercise Intervention for Multiple Sclerosis

N/A

Recruiting

Led By Dawn Ehde, PhD

Research Sponsored by University of Washington

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18 or older

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, weeks 13 and 26

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to test if a phone app can help patients with multiple sclerosis who don't exercise much to become more active.

Who is the study for?

This trial is for adults over 18 with Multiple Sclerosis who can walk without help but are not very active (less than 150 minutes of exercise per week). They must have an iPhone or Android phone to use the study app and cannot be at high risk of falling or have other conditions that make exercising unsafe.

What is being tested?

The study tests a phone-based app called ExerciseRx designed to increase physical activity in people with MS. Participants will use this app, which aims to promote more movement through personalized guidance and tracking.

What are the potential side effects?

Since the intervention involves increased physical activity, potential side effects may include muscle soreness, fatigue, and an increased risk of falls for those predisposed. However, individuals at higher fall risk are excluded from the trial.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, weeks 13 and 26

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, weeks 13 and 26

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, weeks 13 and 26 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Physical activity: daily average step count

Secondary study objectives

Activity volume

Depressive symptom severity - PROMIS Depression Short Form 8a

Fatigue - PROMIS Fatigue-MS Short Form 8a

+7 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intervention ExerciseRx-MSExperimental Treatment1 Intervention

Participants use the ExerciseRx app to meet personalized daily step targets and weekly goals. They will receive MS Exercise and Physical Activity Recommendations and complete in-app surveys about barriers to being active and physical activity level. The ExerciseRx app will adjust the personalized step count goals based on percentage met of the previous week goal and providers will send supportive messages based on participant activity. Participants will complete validated self-report assessments. Providers may also provide participants with additional guidance, make referrals, or schedule telemedicine or in-person clinic follow ups if needed to support the participant's physical activity progression.

Group II: Usual careActive Control1 Intervention

Participants receive MS Exercise and Physical Activity Recommendations, will continue typical physical activity, and complete validated self-report assessments. At the end of 26 weeks, staff will offer the participants the ExerciseRx intervention protocol.

0 / 1Eligibility criteria met