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Alpha-2 Adrenergic Agonist
Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
N/A
Waitlist Available
Led By Joseph I. Markoff, Ph.D,M.D
Research Sponsored by Philadelphia Eye Associates
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group
All Individual Drugs Already Approved
Approved for 10 Other Conditions
Summary
The Purpose of This Study is to Determine if Taking an Over the Counter Non-Steroidal Anti-Inflammatory(Ibuprofen)has an Effect on Eye Pressure in Patients using Brimonidine(Alphagan)and Latanoprost(Xalatan) eye drops.
Eligible Conditions
- Ocular Hypertension
- Glaucoma
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.
Trial Design
3Treatment groups
Active Control
Group I: LatanoprostActive Control2 Interventions
to determine whether commonly used OTC non-steroidal anti-inflammatory agents taken orally has any effect on the ability of either latanoprost or brimonidine to lower high eye pressure
Group II: BrimonidineActive Control2 Interventions
to determine whether commonly used OTC non-steroidal anti-inflammatory agents taken orally has any effect on the ability of either latanoprost or brimonidine to lower high eye pressure
Group III: ibuprofenActive Control2 Interventions
to determine whether commonly used OTC non-steroidal anti-inflammatory agents taken orally has any effect on the ability of either latanoprost or brimonidine to lower high eye pressure
Find a Location
Who is running the clinical trial?
Philadelphia Eye AssociatesLead Sponsor
1 Previous Clinical Trials
PfizerIndustry Sponsor
4,675 Previous Clinical Trials
28,717,131 Total Patients Enrolled
10 Trials studying Ocular Hypertension
2,699 Patients Enrolled for Ocular Hypertension
Joseph I. Markoff, Ph.D,M.DPrincipal InvestigatorPhiladelphia Eye Associates