Potassium-Restricted Diet for Hyperkalemia
(EvoKe-HD Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

No Placebo Group

Trial Summary

What is the purpose of this trial?EvoKe-HD is a pilot randomized controlled trial to assess the feasibility and potential for efficacy of a novel dietary approach to hyperkalemia. Contrary to the traditional recommendations limiting the intake of high-potassium whole foods, such as fruits and vegetables, the investigators propose to switch the focus to foods containing potassium that is readily absorbed by the body (high bioavailability), such as potassium from additives, processed meats, milk, fruit juices and sugary drinks.

Eligibility Criteria

This trial is for adults who speak French or English, have had at least two high potassium blood tests in the last 3 months, and regularly attend hemodialysis sessions. It's not for those with limited control over their diet, a life expectancy under six months, or significant cognitive issues.

Inclusion Criteria

Your blood test results showed high potassium levels at least two times in the past 3 months before dialysis.

I have been on hemodialysis 3 times a week for at least 3 months.

I can speak and understand either French or English.

+3 more

Exclusion Criteria

The doctors don't think you will live longer than 6 months.

You do not have control over what you eat, for example if you live in a nursing home where your meals are chosen for you.

You have trouble understanding dietary recommendations due to a serious problem with thinking and remembering.

Participant Groups

The EvoKe-HD study is testing a new dietary method to manage high potassium levels by limiting foods with easily absorbed potassium versus the traditional approach of avoiding high-potassium whole foods.

2Treatment groups

Experimental Treatment

Active Control

Group I: Restriction high bioavailability potassium sourcesExperimental Treatment1 Intervention

Participants will be asked to identify and avoid food items with potassium additives by revising the ingredient lists of the grocery products they consume. They will also be asked to reduce two sources of high bioavailability potassium, such as meat, milk, fruit juices, processed potatoes or coffee.

Group II: ControlActive Control1 Intervention

Participants will be asked to reduce the intake of food items with high total potassium content. A list of moderate-to-high potassium food items will be provided to the participants.