Robotic Leg Movements for Spinal Cord Injury

Palo Alto (17 mi)

Age: Any Age

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Recruiting

Sponsor: Methodist Rehabilitation Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This study seeks to evaluate whether the speed (cadence) of lower extremity robotic movement has an impact on orthostatic hypotension and upright tolerance when training with the ErigoPro robotic tilt-stepper. It is hypothesized more frequent short-lasting leg movements (faster cadence) reduces the occurrence/severity of orthostatic hypotension better than less frequent longer-lasting leg movements (slower cadence).

Eligibility Criteria

This trial is for individuals aged 16-70 with recent spinal cord injuries (SCI) who experience low blood pressure when standing, weighing less than 297 lbs with leg lengths of 29" - 39". It's not for those with weight-bearing issues, skin lesions where the device fits, uncontrolled diabetes, severe joint contractures in lower limbs, or increased pain/spasticity during leg movements.

Treatment Details

The study tests if different speeds of robotic leg movements using ErigoPro can help manage orthostatic hypotension—low blood pressure upon standing—in people with subacute SCI. It compares faster cadence to slower cadence to see which better prevents or reduces these drops in blood pressure.

1Treatment groups

Experimental Treatment

Group I: TreatmentExperimental Treatment1 Intervention

Progressive elevation (0 degrees, 25 degrees, 50 degrees, 75 degrees; x2 minutes in each position) while on robotic tilt-stepper at the cadence of 0, 40, and 80 steps/minute.