Milk Consumption for Influenza Detection

Recruiting in Palo Alto (17 mi)

Overseen byDaniel Graciaa, MD, MPH, MSc

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Emory University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine whether drinking pasteurized milk (milk heated to kill harmful germs) that contains inactive particles of a flu virus called A(H5) could lead to the detection of the virus in the nose or throat. Inactive particles are not capable of causing disease. The results will help the Centers for Disease Control and Prevention (CDC) better understand how milk consumption could affect flu surveillance. We also want to see if the body produces antibodies in response to this milk consumption.

Research Team

Daniel Graciaa, MD, MPH, MSc

Principal Investigator

Emory University

Eligibility Criteria

This study is for individuals who are healthy and interested in helping the CDC understand flu surveillance. Participants should not have any current illness, especially gastroenteritis or influenza, to avoid confusion with the trial's outcomes.

Inclusion Criteria

I am between 18 and 64 years old.

I understand English, can give consent, and can follow the study plan.

BMI ≤ 35 kg/m2

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Exclusion Criteria

I have taken flu medication in the last 14 days.

Current pregnancy or breastfeeding

History of allergy or intolerance to milk or milk alternatives

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Treatment Details

Interventions

A(H5) Virus in Pasteurized Milk (Virus Therapy)

Trial OverviewThe trial is testing if drinking pasteurized milk containing inactive H5N1 flu virus particles leads to detectable levels of the virus in the nose or throat and if it prompts an antibody response without causing disease.

Participant Groups

2Treatment groups

Experimental Treatment

Group I: 3-Day GroupExperimental Treatment1 Intervention

Participants will consume 250 mL of pasteurized commercial milk for a total of 3 daily consecutive visits.

Group II: 1-Day GroupExperimental Treatment1 Intervention

Participants will consume 250 mL of pasteurized commercial milk at a study visit.