Air Filtration for COPD

Recruiting in Palo Alto (17 mi)

Overseen byZane Elfessi, PharmD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Illinois Institute of Technology

Approved in 2 Jurisdictions

Trial Summary

What is the purpose of this trial?

The goal of this study is to investigate the effectiveness of stand-alone air filtration for improving indoor air quality (IAQ) and chronic obstructive pulmonary disease (COPD) outcomes in a high-risk urban cohort of 80 U.S. military veterans with COPD. Secondary goals of the study are to (1) investigate housing-related factors that may contribute to COPD exacerbation, (2) investigate the utility of using low-cost sensors for indoor air pollution epidemiology studies and for providing actionable or useful information on the quality of their indoor air to patients and their physicians, and (3) evaluate the costs and benefits of using stand-alone air filtration to improve IAQ and COPD outcomes.

Research Team

Kaveeta Jagota

Principal Investigator

Jesse Brown VA Medical Center

Israel Rubinstein, MD

Principal Investigator

Jesse Brown VA Medical Center

Mohammad Heidarinejad, PhD

Principal Investigator

Illinois Institute of Technology

Zane Elfessi, PharmD

Principal Investigator

Jesse Brown VA Medical Center

Eligibility Criteria

This trial is for U.S. military veterans aged 18 and older who have COPD, live in Chicago, can consent, speak English, have stable housing for over 6 months, can communicate by phone, are fully vaccinated against COVID-19 and receive care at JBVAMC. Those with a life expectancy under 6 months or hazardous home conditions cannot join.

Inclusion Criteria

I am between 18 and 90 years old.

English speaking and writing

Able to provide consent

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Exclusion Criteria

Concomitant operation of a non-study air cleaner and alike by a participant in his/her current residence at any time during the course of the trial constitutes protocol violation leading to disqualification of said participant from the study

I am receiving care at home to manage my symptoms.

People who already have an air purifier or similar device in their home will not be included in the screening.

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Treatment Details

Interventions

Air cleaner (Other)

Trial OverviewThe study tests if stand-alone air filters improve indoor air quality and health outcomes for veterans with COPD. It also examines housing factors affecting COPD exacerbation, the use of low-cost sensors to monitor indoor pollution, and the cost-effectiveness of using air filters.

Participant Groups

2Treatment groups

Active Control

Placebo Group

Group I: InterventionActive Control1 Intervention

an air cleaner with HEPA and carbon filter installed

Group II: PlaceboPlacebo Group1 Intervention

an air cleaner with the primary filter removed