Education on Lung Cancer Screening for Smokers

Recruiting in Palo Alto (17 mi)

Overseen by Robert J. Volk

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: M.D. Anderson Cancer Center

Disqualifiers: Lung cancer

No Placebo Group

Trial Summary

What is the purpose of this trial?

This implementation study will examine the best ways to refer heavy smokers to information about lung cancer screening.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Educational Intervention, PRE-ACT Model, Patient Navigator Model for lung cancer screening?

Research shows that interventions focusing on education and patient navigation can help improve lung cancer screening rates, especially among racially and ethnically diverse groups. Patient navigation, which involves guiding patients through the healthcare system, has been shown to reduce barriers and increase participation in lung cancer screening. ^{1 2 3 4 5}

Is the educational intervention for lung cancer screening safe for humans?

The educational intervention, including patient navigation and providing educational materials, has been used safely in studies to help people understand and participate in lung cancer screening. No safety concerns have been reported in these studies. ^{5 6 7 8 9}

How does the education on lung cancer screening for smokers differ from other treatments for lung cancer?

This treatment is unique because it focuses on educating smokers about lung cancer screening, using patient navigation and community-based educational interventions to increase awareness and adherence to screening, rather than directly treating lung cancer itself. It aims to improve screening rates and reduce fear and worry about lung cancer, which is different from traditional treatments that focus on medical or surgical interventions for diagnosed cancer. ^{10 11 12 13 14}

Research Team

Robert J. Volk

Principal Investigator

M.D. Anderson Cancer Center

Eligibility Criteria

This trial is for English-speaking staff members of a quitline, aged between 55-80 years, who have smoked the equivalent of a pack a day for at least 30 years. It's also open to current smokers or those who've quit within the last 15 years. People with a history of lung cancer cannot participate.

Inclusion Criteria

I am over 18 and work for a quitline.

English-speaking

I am currently smoking or quit smoking less than 15 years ago.

Exclusion Criteria

I have been diagnosed with lung cancer.

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Educational Intervention

Call center staff undergo a 60-minute educational session

1 week

1 session (in-person or virtual)

Referral and Questionnaire

Participants are referred to lung cancer screening educational materials and complete questionnaires

6 months

Questionnaires at 1 week and 6 months

Follow-up

Participants are monitored for effectiveness and reach of the educational intervention

Up to 4 years

Treatment Details

Interventions

• Educational Intervention (Behavioural Intervention)

Trial Overview The study is testing educational interventions and surveys to determine effective methods for informing heavy smokers about lung cancer screening options through tobacco quitlines.

Participant Groups

Group I: Callers substudy (LCS educational materials, questionnaire) Experimental Treatment 2 Interventions

Participants are referred to lung cancer screening educational materials. Participants also complete questionnaires at 1 week and 6 months after referral to educational materials.

Group II: Call center staff (educational intervention) Experimental Treatment 2 Interventions

Participants undergo training consisting of a 60-minute educational session.

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

M D Anderson Cancer Center Houston, TX

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials

3107

Patients Recruited

1,813,000+

National Cancer Institute (NCI)

Collaborator

Trials

14080

Patients Recruited

41,180,000+

Findings from Research

Lung cancer screening (LCS) is effective in reducing lung cancer mortality among high-risk smokers, but its adoption is limited, especially among racially and ethnically minoritized groups, highlighting a significant health disparity.

Interventions that streamlined the LCS process at clinics were found to be the most effective, while community-level efforts focused on education showed promise in engaging minoritized populations, indicating a need for more targeted research and standardized outcomes in future studies.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Interventions to improve lung cancer screening among racially and ethnically minoritized groups: A scoping review. Nam, J., Krishnan, G., Shofer, S., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Adherence to Radiology Recommendations in a Clinical CT Lung Screening Program. Alshora, S., McKee, BJ., Regis, SM., et al.[2018]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Pilot Study of an Encounter Decision Aid for Lung Cancer Screening. Ito Fukunaga, M., Balwan, A., Janis, JA., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

An Analysis of Lung Cancer Screening Beliefs and Practice Patterns for Community Providers Compared to Academic Providers. Khairy, M., Duong, DK., Shariff-Marco, S., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Assessing Barriers and Facilitators to Lung Cancer Screening: Initial Findings from a Patient Navigation Intervention. Lee, SJC., Lee, J., Zhu, H., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Quantifying Benefits and Harms of Lung Cancer Screening in an Underserved Population: Results From a Prospective Study. Erkmen, CP., Randhawa, S., Patterson, F., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Provider and patient perspectives to improve lung cancer screening with low-dose computed tomography 5 years after Medicare coverage: a qualitative study. Martinez, MC., Stults, CD., Li, J.[2022]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Understanding lung cancer screening behavior: Racial, gender, and geographic differences among Indiana long-term smokers. Carter-Harris, L., Slaven, JE., Monahan, PO., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The tobacco quitline setting as a teachable moment: The Educating Quitline Users About Lung (EQUAL) cancer screening randomized trial. Webster, M., Whealan, J., Williams, RM., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Adapting Community Educational Programs During the COVID-19 Pandemic: Comparing the Feasibility and Efficacy of a Lung Cancer Screening Educational Intervention by Mode of Delivery. Bouchard, EG., Saad-Harfouche, FG., Clark, N., et al.[2023]

A systematic review of 10 randomized controlled trials and 3 observational studies found that smoking cessation interventions during lung cancer screening significantly increased quit rates compared to usual care, with an odds ratio of 2.01.

Intensive interventions, defined as three or more behavioral counseling sessions, were particularly effective, showing an odds ratio of 2.11 for higher quit rates compared to usual care, while non-intensive interventions did not demonstrate a significant advantage.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Strategies to deliver smoking cessation interventions during targeted lung health screening - a systematic review and meta-analysis. Williams, PJ., Philip, KE., Alghamdi, SM., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Risk perceptions among participants undergoing lung cancer screening: baseline results from the National Lung Screening Trial. Park, ER., Ostroff, JS., Rakowski, W., et al.[2022]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patient navigation for lung cancer screening in an urban safety-net system: Protocol for a pragmatic randomized clinical trial. Gerber, DE., Hamann, HA., Santini, NO., et al.[2023]

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patient navigation for lung cancer screening among current smokers in community health centers a randomized controlled trial. Percac-Lima, S., Ashburner, JM., Rigotti, NA., et al.[2019]

References

1. Ireland pubmed.ncbi.nlm.nih.gov

Interventions to improve lung cancer screening among racially and ethnically minoritized groups: A scoping review. [2023]

2. United States pubmed.ncbi.nlm.nih.gov

Adherence to Radiology Recommendations in a Clinical CT Lung Screening Program. [2018]

3. England pubmed.ncbi.nlm.nih.gov

Pilot Study of an Encounter Decision Aid for Lung Cancer Screening. [2023]

4. United States pubmed.ncbi.nlm.nih.gov

An Analysis of Lung Cancer Screening Beliefs and Practice Patterns for Community Providers Compared to Academic Providers. [2023]

5. United States pubmed.ncbi.nlm.nih.gov

Assessing Barriers and Facilitators to Lung Cancer Screening: Initial Findings from a Patient Navigation Intervention. [2023]

6. United States pubmed.ncbi.nlm.nih.gov

Quantifying Benefits and Harms of Lung Cancer Screening in an Underserved Population: Results From a Prospective Study. [2023]

7. England pubmed.ncbi.nlm.nih.gov

Provider and patient perspectives to improve lung cancer screening with low-dose computed tomography 5 years after Medicare coverage: a qualitative study. [2022]

8. United States pubmed.ncbi.nlm.nih.gov

Understanding lung cancer screening behavior: Racial, gender, and geographic differences among Indiana long-term smokers. [2023]

9. England pubmed.ncbi.nlm.nih.gov

The tobacco quitline setting as a teachable moment: The Educating Quitline Users About Lung (EQUAL) cancer screening randomized trial. [2023]

10. England pubmed.ncbi.nlm.nih.gov

Adapting Community Educational Programs During the COVID-19 Pandemic: Comparing the Feasibility and Efficacy of a Lung Cancer Screening Educational Intervention by Mode of Delivery. [2023]

11. England pubmed.ncbi.nlm.nih.gov

Strategies to deliver smoking cessation interventions during targeted lung health screening - a systematic review and meta-analysis. [2023]

12. England pubmed.ncbi.nlm.nih.gov

Risk perceptions among participants undergoing lung cancer screening: baseline results from the National Lung Screening Trial. [2022]

13. United States pubmed.ncbi.nlm.nih.gov

Patient navigation for lung cancer screening in an urban safety-net system: Protocol for a pragmatic randomized clinical trial. [2023]

14. United States pubmed.ncbi.nlm.nih.gov

Patient navigation for lung cancer screening among current smokers in community health centers a randomized controlled trial. [2019]