Time-Restricted Eating for Metabolic Syndrome in Postmenopausal Women
Trial Summary
What is the purpose of this trial?
This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you are on hormone therapy or ADHD medications, you would not be eligible to participate.
What data supports the effectiveness of the treatment Time-Restricted Eating for Metabolic Syndrome in Postmenopausal Women?
Research shows that time-restricted eating (TRE) can help improve weight, blood pressure, and cholesterol levels in people with metabolic syndrome. Studies have found that TRE can enhance cardiometabolic health, even when combined with standard medical treatments like statins and blood pressure medications.12345
Is time-restricted eating safe for humans?
How is the treatment Time-Restricted Eating different from other treatments for metabolic syndrome?
Time-Restricted Eating (TRE) is unique because it focuses on limiting the time window for eating each day, rather than changing what or how much you eat. This approach can improve metabolic health by aligning eating patterns with the body's natural circadian rhythms, potentially enhancing the effects of standard medications like statins and blood pressure drugs.12346
Eligibility Criteria
This trial is for postmenopausal women aged 45-65 who are prediabetic or show at least two signs of metabolic syndrome and lead a sedentary lifestyle. It's not suitable for those with significant sleep disruptions, psychiatric disorders, heart disease, uncontrolled sleep issues, heavy alcohol use, eating disorders, diabetes, extreme sleeping patterns or those doing shift work.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Baseline data collection including food timing, activity/sleep, and metabolic parameters
Treatment
Participants are randomized to either the TRF intervention or no TRF for 16 weeks. TRF group self-selects a 10-hour eating window.
Follow-up
Participants are monitored for changes in metabolic and anthropometric measurements post-intervention
Treatment Details
Interventions
- Time-Restricted Feeding (Behavioral Intervention)