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Procedure

Nerve Transfer Surgery for Stroke Recovery

N/A
Recruiting
Led By Jennifer Hong, Dr.
Research Sponsored by Dartmouth-Hitchcock Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
History of ischemic or hemorrhagic stroke with resultant arm paresis that has ceased to improve within 1-5 years of rehabilitation.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months with visits at baseline and months 2, 4, 8, and 12 months after surgery.
Awards & highlights
No Placebo-Only Group

Summary

This trial looks at how well surgery to transfer a nerve can improve arm/leg function after a stroke.

Who is the study for?
This trial is for stroke survivors with arm weakness or paralysis who haven't seen improvement after 1-5 years of rehab. It's not suitable for pregnant individuals.
What is being tested?
The study tests a surgical procedure called contralateral C7 root transfer, aiming to improve arm function in patients with spastic hemiparesis due to stroke.
What are the potential side effects?
Potential side effects may include discomfort at the surgery site, infection risk, nerve damage, and possibly limited movement improvements.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I had a stroke that left my arm weak, and it hasn't gotten better in 1-5 years despite therapy.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months with visits at baseline and months 2, 4, 8, and 12 months after surgery.
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months with visits at baseline and months 2, 4, 8, and 12 months after surgery. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change from baseline in arm function, as measured by the Fugl-Meyer upper-extremity scale.

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Contralateral C7 root transfer for the treatment of spastic hemiparesis.Experimental Treatment1 Intervention
The C7 nerve root transfer will occur to the patients on this arm.

Find a Location

Who is running the clinical trial?

Dartmouth-Hitchcock Medical CenterLead Sponsor
537 Previous Clinical Trials
2,539,621 Total Patients Enrolled
Jennifer Hong, Dr.Principal InvestigatorDartmouth-Hitchcock Medical Center
~43 spots leftby Mar 2027