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Behavioral Intervention

Cognitive Bias Modification for Obsessive-Compulsive Disorder

N/A
Recruiting
Led By Hanjoo Lee, PhD
Research Sponsored by Han Joo Lee
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged 18 or higher
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-training (before 1st training session), post-training (at the end of 6th training session, 3 weeks after the 1st training session on average), 1-month follow-up (1 month after the 6th training session)
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to study the effects of a treatment targeting a cognitive bias called Thought-Action-Fusion (TAF) on improving symptoms of obsessive-compulsive disorder (OCD). TAF is a

Who is the study for?
This trial is for college individuals with Obsessive-Compulsive Disorder (OCD) who experience Thought-Action-Fusion, where they believe unwanted thoughts are morally wrong or likely to become real. Specific eligibility criteria details were not provided.
What is being tested?
The study tests a personalized cognitive bias modification program targeting Thought-Action-Fusion biases in OCD patients. It aims to see if changing these thought patterns can improve OCD symptoms over multiple sessions.
What are the potential side effects?
Potential side effects are not specified but may include discomfort from confronting personal thoughts and increased awareness of one's own thought-action fusion biases during the intervention.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-training (before 1st training session), post-training (at the end of 6th training session, 3 weeks after the 1st training session on average), 1-month follow-up (1 month after the 6th training session)
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-training (before 1st training session), post-training (at the end of 6th training session, 3 weeks after the 1st training session on average), 1-month follow-up (1 month after the 6th training session) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Dimensional Obsessive-Compulsive Scale (DOCS) at Pre-, Post-, and 1MFU
Thought-Action-Fusion Scale (TAFS) at Pre-, Post-, and 1MFU
Secondary study objectives
Depression, Anxiety, and Stress Scale (DASS-21) at Pre-, Post-, and 1MFU

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Cognitive Bias Modification for Thought-Action-Fusion (CBM-TAF)Experimental Treatment1 Intervention
CBM-TAF will employ an ambiguous sentence-completion task, where participants have to fill in a missing letter in a fragmented word and resolve emotional ambiguity of a given scenario. At the beginning of each training session, participants will watch a brief animated video about TAF, OCD, and modifying TAF. Each training session will consist of 40 scenarios, which will take about 20 minutes to complete. There will be a total of 6 sessions (2x/week for 3 weeks).
Group II: Cognitive Bias Modification for Stress Management Psychoeducation (CBM-SMP)Active Control1 Intervention
Similar to CBM-TAF, CBM-SMP will employ an ambiguous sentence-completion task, where participants have to fill in a missing letter in a fragmented word. However, the content of scenarios in CBM-SMP will focus on general stress management techniques. At the beginning of each training session, participants will watch a brief animated video about OCD and stress management techniques. Each training session will consist of 40 scenarios, which will take about 20 minutes to complete. There will be a total of 6 sessions (2x/week for 3 weeks).
Group III: Waitlist (WL)Active Control1 Intervention
Participants in WL group will only complete weekly assessment measures without engaging in any training sessions.

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Who is running the clinical trial?

Han Joo LeeLead Sponsor
Psi ChiUNKNOWN
5 Previous Clinical Trials
266 Total Patients Enrolled
Hanjoo Lee, PhDPrincipal InvestigatorUniversity of Wisconsin, Milwaukee
~54 spots leftby May 2026