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Neuromodulation

Neuromodulation for Obsessive-Compulsive Disorder

N/A
Recruiting
Research Sponsored by Boston University Charles River Campus
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months after intervention

Summary

This trial is researching a new method to reduce OCD symptoms, with minimal side effects, using brain wave recordings to repetitively modulate an area of the brain affected by OCD.

Who is the study for?
This trial is for adults with OCD who score at least 16 on the YBOCS, can consent to participate, and follow study rules. It's not for those with severe depression, pregnancy, metal head implants, electronic devices in body, vision issues despite correction, claustrophobia or neurological disorders like epilepsy.
What is being tested?
The study tests a new non-invasive neuromodulation technique using HD-tACS guided by EEG to reduce OCD symptoms quickly (within five days) and sustainably (up to three months). The focus is on modulating brain rhythms in the OFC that are linked with reward and decision-making.
What are the potential side effects?
Since this method is non-invasive and well-tolerated based on preliminary data, minimal side effects are expected. However, specific side effects aren't detailed here; they may include discomfort from wearing stimulation equipment or mild headaches.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months after intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months after intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Secondary study objectives
YBOCS

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active HD-tACSActive Control1 Intervention
HD-tACS of OFC
Group II: Sham HD-tACSPlacebo Group1 Intervention
HD-tACS of OFC

Find a Location

Who is running the clinical trial?

Boston University Charles River CampusLead Sponsor
120 Previous Clinical Trials
13,277 Total Patients Enrolled
2 Trials studying Obsessive-Compulsive Disorder
100 Patients Enrolled for Obsessive-Compulsive Disorder
~60 spots leftby Aug 2026
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